Mediterranean semi-arid plant Astragalus armatus as a source of bioactive galactomannan
A water-soluble polysaccharide fraction (WSPF) was extracted and purified from Astragalus armatus Lam. (Fabaceae), a spontaneous plant found in North Algerian Sahara. The structural features of WSPF were evaluated by colorimetric assays, Fourier transform infrared (FTIR) spectroscopy, high performan...
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| Veröffentlicht in: | Bioactive carbohydrates and dietary fibre 2015-01, Vol.5 (1), p.10-18 |
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| container_title | Bioactive carbohydrates and dietary fibre |
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| creator | Boual, Zakaria Pierre, Guillaume Delattre, Cédric Benaoun, Fatima Petit, Emmanuel Gardarin, Christine Michaud, Philippe El Hadj, Mohamed Didi Ould |
| description | A water-soluble polysaccharide fraction (WSPF) was extracted and purified from Astragalus armatus Lam. (Fabaceae), a spontaneous plant found in North Algerian Sahara. The structural features of WSPF were evaluated by colorimetric assays, Fourier transform infrared (FTIR) spectroscopy, high performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) and gas chromatography coupled to mass spectrometry (GC/MS). WSPF was a galactomannan-rich fraction, with a β-(1,4)-d-manp backbone with α-(1,6)-d-galp branches, and a Man:Gal ratio of 1.13. Besides, the anti-complement activity and the antioxidant potential (DPPH and hydroxyl radicals) of WSPF were evaluated. The results exhibited an anti-complementary activity, with an IC50 value of 0.39mg/mL of the fraction, better than for heparin (0.58mg/mL). Moreover, WSPF possessed a notable antioxidant activity on DPPH radical with an IC50 of 330µg/mL.
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•Astragalus armatus is an exotic and underexploited plant from Algerian Sahara.•A water soluble polysaccharide fraction (WSPF) was extracted from A. armatus.•WSPF was a galactomannan-rich fraction with a Manp:Galp ratio of 1.13.•An anti-complementary activity was observed, with an IC50 value of 390µg/mL.•A notable antioxidant activity was observed with an IC50 value of 330µg/mL. |
| doi_str_mv | 10.1016/j.bcdf.2014.11.002 |
| format | Article |
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•Astragalus armatus is an exotic and underexploited plant from Algerian Sahara.•A water soluble polysaccharide fraction (WSPF) was extracted from A. armatus.•WSPF was a galactomannan-rich fraction with a Manp:Galp ratio of 1.13.•An anti-complementary activity was observed, with an IC50 value of 390µg/mL.•A notable antioxidant activity was observed with an IC50 value of 330µg/mL.</description><identifier>ISSN: 2212-6198</identifier><identifier>EISSN: 2212-6198</identifier><identifier>DOI: 10.1016/j.bcdf.2014.11.002</identifier><language>eng</language><publisher>Elsevier Ltd</publisher><subject>Anticomplement ; Antioxidant ; Astragalus armatus ; Biochemistry ; Biochemistry, Molecular Biology ; Chemical and Process Engineering ; Engineering Sciences ; Fabaceae ; Galactomannan ; Life Sciences</subject><ispartof>Bioactive carbohydrates and dietary fibre, 2015-01, Vol.5 (1), p.10-18</ispartof><rights>2014 Elsevier Ltd</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-ec4659683b808ba84e8d45ef53754a8835a07d7dd4f6e62111dca0ed8194aeb53</citedby><cites>FETCH-LOGICAL-c385t-ec4659683b808ba84e8d45ef53754a8835a07d7dd4f6e62111dca0ed8194aeb53</cites><orcidid>0000-0003-1533-6909 ; 0000-0003-3605-1929 ; 0000-0002-6677-4549 ; 0000-0001-9919-7058</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://uca.hal.science/hal-01660708$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Boual, Zakaria</creatorcontrib><creatorcontrib>Pierre, Guillaume</creatorcontrib><creatorcontrib>Delattre, Cédric</creatorcontrib><creatorcontrib>Benaoun, Fatima</creatorcontrib><creatorcontrib>Petit, Emmanuel</creatorcontrib><creatorcontrib>Gardarin, Christine</creatorcontrib><creatorcontrib>Michaud, Philippe</creatorcontrib><creatorcontrib>El Hadj, Mohamed Didi Ould</creatorcontrib><title>Mediterranean semi-arid plant Astragalus armatus as a source of bioactive galactomannan</title><title>Bioactive carbohydrates and dietary fibre</title><description>A water-soluble polysaccharide fraction (WSPF) was extracted and purified from Astragalus armatus Lam. (Fabaceae), a spontaneous plant found in North Algerian Sahara. The structural features of WSPF were evaluated by colorimetric assays, Fourier transform infrared (FTIR) spectroscopy, high performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) and gas chromatography coupled to mass spectrometry (GC/MS). WSPF was a galactomannan-rich fraction, with a β-(1,4)-d-manp backbone with α-(1,6)-d-galp branches, and a Man:Gal ratio of 1.13. Besides, the anti-complement activity and the antioxidant potential (DPPH and hydroxyl radicals) of WSPF were evaluated. The results exhibited an anti-complementary activity, with an IC50 value of 0.39mg/mL of the fraction, better than for heparin (0.58mg/mL). Moreover, WSPF possessed a notable antioxidant activity on DPPH radical with an IC50 of 330µg/mL.
[Display omitted]
•Astragalus armatus is an exotic and underexploited plant from Algerian Sahara.•A water soluble polysaccharide fraction (WSPF) was extracted from A. armatus.•WSPF was a galactomannan-rich fraction with a Manp:Galp ratio of 1.13.•An anti-complementary activity was observed, with an IC50 value of 390µg/mL.•A notable antioxidant activity was observed with an IC50 value of 330µg/mL.</description><subject>Anticomplement</subject><subject>Antioxidant</subject><subject>Astragalus armatus</subject><subject>Biochemistry</subject><subject>Biochemistry, Molecular Biology</subject><subject>Chemical and Process Engineering</subject><subject>Engineering Sciences</subject><subject>Fabaceae</subject><subject>Galactomannan</subject><subject>Life Sciences</subject><issn>2212-6198</issn><issn>2212-6198</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kE9LAzEQxYMoWGq_gKdcPeyayf7LgpdS1AoVL4rHMJvMasp2tyTbgt_eLBXxJAy8x_DewPwYuwaRgoDydps2xrapFJCnAKkQ8ozNpASZlFCr8z_-ki1C2AohQEItsmzG3p_JupG8x56w54F2LkHvLN932I98GUaPH9gdAke_w3HSODwMB2-IDy1v3IBmdEfiMRbdsMO-x_6KXbTYBVr86Jy9Pdy_rtbJ5uXxabXcJCZTxZiQycuiLlXWKKEaVDkpmxfUFllV5KhUVqCobGVt3pZUSgCwBgVZBXWO1BTZnN2c7n5ip_fe7dB_6QGdXi83etpFQKWohDpCzMpT1vghBE_tbwGEnkjqrZ5I6omkBtCRZCzdnUoUvzg68joYR72J2DyZUdvB_Vf_BoMbfCE</recordid><startdate>201501</startdate><enddate>201501</enddate><creator>Boual, Zakaria</creator><creator>Pierre, Guillaume</creator><creator>Delattre, Cédric</creator><creator>Benaoun, Fatima</creator><creator>Petit, Emmanuel</creator><creator>Gardarin, Christine</creator><creator>Michaud, Philippe</creator><creator>El Hadj, Mohamed Didi Ould</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>AAYXX</scope><scope>CITATION</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0003-1533-6909</orcidid><orcidid>https://orcid.org/0000-0003-3605-1929</orcidid><orcidid>https://orcid.org/0000-0002-6677-4549</orcidid><orcidid>https://orcid.org/0000-0001-9919-7058</orcidid></search><sort><creationdate>201501</creationdate><title>Mediterranean semi-arid plant Astragalus armatus as a source of bioactive galactomannan</title><author>Boual, Zakaria ; Pierre, Guillaume ; Delattre, Cédric ; Benaoun, Fatima ; Petit, Emmanuel ; Gardarin, Christine ; Michaud, Philippe ; El Hadj, Mohamed Didi Ould</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-ec4659683b808ba84e8d45ef53754a8835a07d7dd4f6e62111dca0ed8194aeb53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Anticomplement</topic><topic>Antioxidant</topic><topic>Astragalus armatus</topic><topic>Biochemistry</topic><topic>Biochemistry, Molecular Biology</topic><topic>Chemical and Process Engineering</topic><topic>Engineering Sciences</topic><topic>Fabaceae</topic><topic>Galactomannan</topic><topic>Life Sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boual, Zakaria</creatorcontrib><creatorcontrib>Pierre, Guillaume</creatorcontrib><creatorcontrib>Delattre, Cédric</creatorcontrib><creatorcontrib>Benaoun, Fatima</creatorcontrib><creatorcontrib>Petit, Emmanuel</creatorcontrib><creatorcontrib>Gardarin, Christine</creatorcontrib><creatorcontrib>Michaud, Philippe</creatorcontrib><creatorcontrib>El Hadj, Mohamed Didi Ould</creatorcontrib><collection>CrossRef</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Bioactive carbohydrates and dietary fibre</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boual, Zakaria</au><au>Pierre, Guillaume</au><au>Delattre, Cédric</au><au>Benaoun, Fatima</au><au>Petit, Emmanuel</au><au>Gardarin, Christine</au><au>Michaud, Philippe</au><au>El Hadj, Mohamed Didi Ould</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mediterranean semi-arid plant Astragalus armatus as a source of bioactive galactomannan</atitle><jtitle>Bioactive carbohydrates and dietary fibre</jtitle><date>2015-01</date><risdate>2015</risdate><volume>5</volume><issue>1</issue><spage>10</spage><epage>18</epage><pages>10-18</pages><issn>2212-6198</issn><eissn>2212-6198</eissn><abstract>A water-soluble polysaccharide fraction (WSPF) was extracted and purified from Astragalus armatus Lam. (Fabaceae), a spontaneous plant found in North Algerian Sahara. The structural features of WSPF were evaluated by colorimetric assays, Fourier transform infrared (FTIR) spectroscopy, high performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) and gas chromatography coupled to mass spectrometry (GC/MS). WSPF was a galactomannan-rich fraction, with a β-(1,4)-d-manp backbone with α-(1,6)-d-galp branches, and a Man:Gal ratio of 1.13. Besides, the anti-complement activity and the antioxidant potential (DPPH and hydroxyl radicals) of WSPF were evaluated. The results exhibited an anti-complementary activity, with an IC50 value of 0.39mg/mL of the fraction, better than for heparin (0.58mg/mL). Moreover, WSPF possessed a notable antioxidant activity on DPPH radical with an IC50 of 330µg/mL.
[Display omitted]
•Astragalus armatus is an exotic and underexploited plant from Algerian Sahara.•A water soluble polysaccharide fraction (WSPF) was extracted from A. armatus.•WSPF was a galactomannan-rich fraction with a Manp:Galp ratio of 1.13.•An anti-complementary activity was observed, with an IC50 value of 390µg/mL.•A notable antioxidant activity was observed with an IC50 value of 330µg/mL.</abstract><pub>Elsevier Ltd</pub><doi>10.1016/j.bcdf.2014.11.002</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-1533-6909</orcidid><orcidid>https://orcid.org/0000-0003-3605-1929</orcidid><orcidid>https://orcid.org/0000-0002-6677-4549</orcidid><orcidid>https://orcid.org/0000-0001-9919-7058</orcidid></addata></record> |
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| subjects | Anticomplement Antioxidant Astragalus armatus Biochemistry Biochemistry, Molecular Biology Chemical and Process Engineering Engineering Sciences Fabaceae Galactomannan Life Sciences |
| title | Mediterranean semi-arid plant Astragalus armatus as a source of bioactive galactomannan |
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