Structure and phylogeny of the crustacean hyperglycemic hormone and its precursor from a hydrothermal vent crustacean: the crab Bythograea thermydron
The structure of a well-known neurohormone involved in homeostasis regulation and stress response, the crustacean hyperglycemic hormone, was investigated in the deep-sea hydrothermal vent crab Bythograea thermydron. The neuropeptide was isolated from neurohemal organs (sinus glands) and its biologic...
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| Veröffentlicht in: | Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2002, Vol.23 (1), p.31-42 |
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| creator | Toullec, Jean-Yves Vinh, Joëlle Le Caer, Jean-Pierre Shillito, Bruce Soyez, Daniel |
| description | The structure of a well-known neurohormone involved in homeostasis regulation and stress response, the crustacean hyperglycemic hormone, was investigated in the deep-sea hydrothermal vent crab
Bythograea thermydron. The neuropeptide was isolated from neurohemal organs (sinus glands) and its biological activity checked using an homologous bioassay. Partial amino acid sequence was established by a combination of Edman chemistry and mass spectrometry. Then, the sequence of the cDNA encoding the hormone precursor was determined. The preprohormone
1
is composed of a 29 amino acid signal peptide, followed by a 41 amino acid associated peptide flanking the 72 amino acid hyperglycemic hormone. Comparison of these data with other known crab hyperglycemic hormone and prohormone sequences was performed using phylogenetic analysis methods. |
| doi_str_mv | 10.1016/S0196-9781(01)00576-9 |
| format | Article |
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Bythograea thermydron. The neuropeptide was isolated from neurohemal organs (sinus glands) and its biological activity checked using an homologous bioassay. Partial amino acid sequence was established by a combination of Edman chemistry and mass spectrometry. Then, the sequence of the cDNA encoding the hormone precursor was determined. The preprohormone
1
is composed of a 29 amino acid signal peptide, followed by a 41 amino acid associated peptide flanking the 72 amino acid hyperglycemic hormone. Comparison of these data with other known crab hyperglycemic hormone and prohormone sequences was performed using phylogenetic analysis methods.</description><identifier>ISSN: 0196-9781</identifier><identifier>EISSN: 1873-5169</identifier><identifier>DOI: 10.1016/S0196-9781(01)00576-9</identifier><identifier>PMID: 11814615</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Amino Acid Sequence ; Animals ; Arthropod Proteins ; Arthropods ; Base Sequence ; Biological Assay ; Blood Glucose - metabolism ; Brachyura ; Bythograea thermydron ; Chemical Sciences ; Chromatography, High Pressure Liquid ; Crustacean hyperglycemic hormone ; DNA, Complementary - metabolism ; Endoproteinase Lys-C (EC 3.4.21.50) ; Enzyme-Linked Immunosorbent Assay ; Hemolymph - metabolism ; Hydrothermal vents ; Invertebrate Hormones ; Life Sciences ; MALDI-TOF mass spectrometry ; Mass Spectrometry ; Molecular Sequence Data ; Nerve Tissue Proteins - chemistry ; Nerve Tissue Proteins - genetics ; Peptides - chemistry ; Phylogeny ; Protein Precursors - chemistry ; Protein Sorting Signals ; Reverse Transcriptase Polymerase Chain Reaction ; RNA - metabolism ; Sequence Analysis, Protein ; Sequence Homology, Amino Acid ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Time Factors ; X-organ-sinus gland complex</subject><ispartof>Peptides (New York, N.Y. : 1980), 2002, Vol.23 (1), p.31-42</ispartof><rights>2002 Elsevier Science Inc.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c426t-efb6ff5b06b21db3f2f7bee29d7a6e9b5d6eff45bc188479aee067a5f5b602bd3</citedby><cites>FETCH-LOGICAL-c426t-efb6ff5b06b21db3f2f7bee29d7a6e9b5d6eff45bc188479aee067a5f5b602bd3</cites><orcidid>0000-0001-7184-2668 ; 0000-0001-7932-3045 ; 0009-0007-5764-9969</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0196978101005769$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11814615$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-01637048$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Toullec, Jean-Yves</creatorcontrib><creatorcontrib>Vinh, Joëlle</creatorcontrib><creatorcontrib>Le Caer, Jean-Pierre</creatorcontrib><creatorcontrib>Shillito, Bruce</creatorcontrib><creatorcontrib>Soyez, Daniel</creatorcontrib><title>Structure and phylogeny of the crustacean hyperglycemic hormone and its precursor from a hydrothermal vent crustacean: the crab Bythograea thermydron</title><title>Peptides (New York, N.Y. : 1980)</title><addtitle>Peptides</addtitle><description>The structure of a well-known neurohormone involved in homeostasis regulation and stress response, the crustacean hyperglycemic hormone, was investigated in the deep-sea hydrothermal vent crab
Bythograea thermydron. The neuropeptide was isolated from neurohemal organs (sinus glands) and its biological activity checked using an homologous bioassay. Partial amino acid sequence was established by a combination of Edman chemistry and mass spectrometry. Then, the sequence of the cDNA encoding the hormone precursor was determined. The preprohormone
1
is composed of a 29 amino acid signal peptide, followed by a 41 amino acid associated peptide flanking the 72 amino acid hyperglycemic hormone. Comparison of these data with other known crab hyperglycemic hormone and prohormone sequences was performed using phylogenetic analysis methods.</description><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Arthropod Proteins</subject><subject>Arthropods</subject><subject>Base Sequence</subject><subject>Biological Assay</subject><subject>Blood Glucose - metabolism</subject><subject>Brachyura</subject><subject>Bythograea thermydron</subject><subject>Chemical Sciences</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Crustacean hyperglycemic hormone</subject><subject>DNA, Complementary - metabolism</subject><subject>Endoproteinase Lys-C (EC 3.4.21.50)</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Hemolymph - metabolism</subject><subject>Hydrothermal vents</subject><subject>Invertebrate Hormones</subject><subject>Life Sciences</subject><subject>MALDI-TOF mass spectrometry</subject><subject>Mass Spectrometry</subject><subject>Molecular Sequence Data</subject><subject>Nerve Tissue Proteins - chemistry</subject><subject>Nerve Tissue Proteins - genetics</subject><subject>Peptides - chemistry</subject><subject>Phylogeny</subject><subject>Protein Precursors - chemistry</subject><subject>Protein Sorting Signals</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>RNA - metabolism</subject><subject>Sequence Analysis, Protein</subject><subject>Sequence Homology, Amino Acid</subject><subject>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</subject><subject>Time Factors</subject><subject>X-organ-sinus gland complex</subject><issn>0196-9781</issn><issn>1873-5169</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAURi0EokPhEUBeIboI-ObHTthUpQKKNBKLwtqynetJUBIPtjNSHoT3xTMZFXZdWbbO9_nqHkJeA3sPDPiHewYNzxpRwzsGV4xVIt2ekA3Uosgq4M1TsnlALsiLEH4xxsqyqZ-TC4AaSg7Vhvy5j342cfZI1dTSfbcMbofTQp2lsUNq_ByiMqgm2i179LthMTj2hnbOj25aU30MdO_RzD44T613I1UJb71LFX5UAz3gFP_r-njuVpp-WmLndl6hoif4mJpekmdWDQFfnc9L8vPL5x-3d9n2-9dvtzfbzJQ5jxlaza2tNOM6h1YXNrdCI-ZNKxTHRlctR2vLShuo61I0CpFxoaoU4SzXbXFJrtbeTg1y7_tR-UU61cu7m608vqVNF4KV9QES-3Zl9979njFEOfbB4DCoCd0cpIAyZ1CIR0GoK1GAYAmsVtB4F4JH-zACMHmULE-S5dFgmkSeJMsm5d6cP5j1iO2_1NlqAq5XANPuDj16GUyPk8G2T5aibF3_yBd_AXd6uw8</recordid><startdate>2002</startdate><enddate>2002</enddate><creator>Toullec, Jean-Yves</creator><creator>Vinh, Joëlle</creator><creator>Le Caer, Jean-Pierre</creator><creator>Shillito, Bruce</creator><creator>Soyez, Daniel</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0001-7184-2668</orcidid><orcidid>https://orcid.org/0000-0001-7932-3045</orcidid><orcidid>https://orcid.org/0009-0007-5764-9969</orcidid></search><sort><creationdate>2002</creationdate><title>Structure and phylogeny of the crustacean hyperglycemic hormone and its precursor from a hydrothermal vent crustacean: the crab Bythograea thermydron</title><author>Toullec, Jean-Yves ; Vinh, Joëlle ; Le Caer, Jean-Pierre ; Shillito, Bruce ; Soyez, Daniel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-efb6ff5b06b21db3f2f7bee29d7a6e9b5d6eff45bc188479aee067a5f5b602bd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Arthropod Proteins</topic><topic>Arthropods</topic><topic>Base Sequence</topic><topic>Biological Assay</topic><topic>Blood Glucose - metabolism</topic><topic>Brachyura</topic><topic>Bythograea thermydron</topic><topic>Chemical Sciences</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Crustacean hyperglycemic hormone</topic><topic>DNA, Complementary - metabolism</topic><topic>Endoproteinase Lys-C (EC 3.4.21.50)</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Hemolymph - metabolism</topic><topic>Hydrothermal vents</topic><topic>Invertebrate Hormones</topic><topic>Life Sciences</topic><topic>MALDI-TOF mass spectrometry</topic><topic>Mass Spectrometry</topic><topic>Molecular Sequence Data</topic><topic>Nerve Tissue Proteins - chemistry</topic><topic>Nerve Tissue Proteins - genetics</topic><topic>Peptides - chemistry</topic><topic>Phylogeny</topic><topic>Protein Precursors - chemistry</topic><topic>Protein Sorting Signals</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>RNA - metabolism</topic><topic>Sequence Analysis, Protein</topic><topic>Sequence Homology, Amino Acid</topic><topic>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</topic><topic>Time Factors</topic><topic>X-organ-sinus gland complex</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Toullec, Jean-Yves</creatorcontrib><creatorcontrib>Vinh, Joëlle</creatorcontrib><creatorcontrib>Le Caer, Jean-Pierre</creatorcontrib><creatorcontrib>Shillito, Bruce</creatorcontrib><creatorcontrib>Soyez, Daniel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Peptides (New York, N.Y. : 1980)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Toullec, Jean-Yves</au><au>Vinh, Joëlle</au><au>Le Caer, Jean-Pierre</au><au>Shillito, Bruce</au><au>Soyez, Daniel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Structure and phylogeny of the crustacean hyperglycemic hormone and its precursor from a hydrothermal vent crustacean: the crab Bythograea thermydron</atitle><jtitle>Peptides (New York, N.Y. : 1980)</jtitle><addtitle>Peptides</addtitle><date>2002</date><risdate>2002</risdate><volume>23</volume><issue>1</issue><spage>31</spage><epage>42</epage><pages>31-42</pages><issn>0196-9781</issn><eissn>1873-5169</eissn><abstract>The structure of a well-known neurohormone involved in homeostasis regulation and stress response, the crustacean hyperglycemic hormone, was investigated in the deep-sea hydrothermal vent crab
Bythograea thermydron. The neuropeptide was isolated from neurohemal organs (sinus glands) and its biological activity checked using an homologous bioassay. Partial amino acid sequence was established by a combination of Edman chemistry and mass spectrometry. Then, the sequence of the cDNA encoding the hormone precursor was determined. The preprohormone
1
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| ispartof | Peptides (New York, N.Y. : 1980), 2002, Vol.23 (1), p.31-42 |
| issn | 0196-9781 1873-5169 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Amino Acid Sequence Animals Arthropod Proteins Arthropods Base Sequence Biological Assay Blood Glucose - metabolism Brachyura Bythograea thermydron Chemical Sciences Chromatography, High Pressure Liquid Crustacean hyperglycemic hormone DNA, Complementary - metabolism Endoproteinase Lys-C (EC 3.4.21.50) Enzyme-Linked Immunosorbent Assay Hemolymph - metabolism Hydrothermal vents Invertebrate Hormones Life Sciences MALDI-TOF mass spectrometry Mass Spectrometry Molecular Sequence Data Nerve Tissue Proteins - chemistry Nerve Tissue Proteins - genetics Peptides - chemistry Phylogeny Protein Precursors - chemistry Protein Sorting Signals Reverse Transcriptase Polymerase Chain Reaction RNA - metabolism Sequence Analysis, Protein Sequence Homology, Amino Acid Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Time Factors X-organ-sinus gland complex |
| title | Structure and phylogeny of the crustacean hyperglycemic hormone and its precursor from a hydrothermal vent crustacean: the crab Bythograea thermydron |
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