Inhibition of ectopic glioma tumor growth by a potent ferrocenyl drug loaded into stealth lipid nanocapsules

Abstract In this work, a novel ferrocenyl complex (ansa-FcdiOH) was assessed for brain tumor therapy through stealth lipid nanocapsules (LNCs). Stealth LNCs, prepared according to a one-step process, showed rapid uptake by cancer cells and extended blood circulation time. The ferrocenyl complex was...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nanomedicine 2014-11, Vol.10 (8), p.1667-1677
Hauptverfasser:	Lainé, Anne-Laure, PhD, Clavreul, Anne, PhD, Rousseau, Audrey, PhD, MD, Tétaud, Clément, Vessieres, Anne, PhD, Garcion, Emmanuel, PhD, Jaouen, Gerard, PhD, Aubert, Léo, Guilbert, Matthieu, Benoit, Jean-Pierre, PhD, Toillon, Robert-Alain, PhD, Passirani, Catherine, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ansa-FcdiOH Cell cycle Cell Cycle - drug effects Cell Line, Tumor Chemical Sciences Drug Carriers - chemistry EPR effect Female Ferrous Compounds - chemistry Ferrous Compounds - therapeutic use Glioma - drug therapy Internal Medicine Life Sciences Nanocapsules - chemistry Nanomedicine Rats Rats, Inbred F344 Reactive Oxygen Species
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!