In cellulo monitoring of quinone reductase activity and reactive oxygen species production during the redox cycling of 1,2 and 1,4 quinones

Quinones are highly reactive molecules that readily undergo either one- or two-electron reduction. One-electron reduction of quinones or their derivatives by enzymes such as cytochrome P450 reductase or other flavoproteins generates unstable semiquinones, which undergo redox cycling in the presence...

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Veröffentlicht in:Free radical biology & medicine 2015-12, Vol.89, p.126-134
Hauptverfasser: Cassagnes, Laure-Estelle, Perio, Pierre, Ferry, Gilles, Moulharat, Natacha, Antoine, Mathias, Gayon, Régis, Boutin, Jean A., Nepveu, Françoise, Reybier, Karine
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