Monocyte-derived Macrophages from Crohn’s Disease Patients Are Impaired in the Ability to Control Intracellular Adherent-Invasive Escherichia coli and Exhibit Disordered Cytokine Secretion Profile

Background: Ileal lesions of Crohn’s disease [CD] patients are colonised by adherent-invasive Escherichia coli [AIEC] able to survive in macrophage cell lines. We analysed the ability of monocyte-derived macrophages [MDM] from CD patients to control AIEC intracellular replication and the pro-inflamm...

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Veröffentlicht in:Journal of Crohn's and colitis 2015-05, Vol.9 (5), p.410-420
Hauptverfasser: Vazeille, Emilie, Buisson, Anthony, Bringer, Marie-Agnès, Goutte, Marion, Ouchchane, Lemlih, Hugot, Jean-Pierre, de Vallée, Amélie, Barnich, Nicolas, Bommelaer, Gilles, Darfeuille-Michaud, Arlette
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Sprache:eng
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