Monocyte-derived Macrophages from Crohn’s Disease Patients Are Impaired in the Ability to Control Intracellular Adherent-Invasive Escherichia coli and Exhibit Disordered Cytokine Secretion Profile
Background: Ileal lesions of Crohn’s disease [CD] patients are colonised by adherent-invasive Escherichia coli [AIEC] able to survive in macrophage cell lines. We analysed the ability of monocyte-derived macrophages [MDM] from CD patients to control AIEC intracellular replication and the pro-inflamm...
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Veröffentlicht in: | Journal of Crohn's and colitis 2015-05, Vol.9 (5), p.410-420 |
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Sprache: | eng |
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