Assessment of formulation robustness for nano-crystalline suspensions using failure mode analysis or derisking approach

[Display omitted] The small particle size of nano-crystalline suspensions can be responsible for their physical instability during drug product preparation (downstream processing), storage and administration. For that purpose, the commercial formulation needs to be sufficiently robust to various tri...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of pharmaceutics 2016-06, Vol.506 (1-2), p.320-331
Hauptverfasser: Nakach, Mostafa, Authelin, Jean-René, Voignier, Cecile, Tadros, Tharwat, Galet, Laurence, Chamayou, Alain
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!