Gold(i)-BODIPY-imidazole bimetallic complexes as new potential anti-inflammatory and anticancer trackable agents
Two new gold(i)-BODIPY-imidazole based trackable therapeutic bimetallic complexes have been synthesized and fully characterized. They display strong antiproliferative properties on several types of cancers including colon, breast, and prostate and one of them presents a significant anti-inflammatory...
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| Veröffentlicht in: | Dalton transactions : an international journal of inorganic chemistry 2017, Vol.46 (25), p.8051-8056 |
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| container_title | Dalton transactions : an international journal of inorganic chemistry |
| container_volume | 46 |
| creator | Trommenschlager, Audrey Chotard, Florian Bertrand, Benoît Amor, Souheila Dondaine, Lucile Picquet, Michel Richard, Philippe Bettaïeb, Ali Le Gendre, Pierre Paul, Catherine Goze, Christine Bodio, Ewen |
| description | Two new gold(i)-BODIPY-imidazole based trackable therapeutic bimetallic complexes have been synthesized and fully characterized. They display strong antiproliferative properties on several types of cancers including colon, breast, and prostate and one of them presents a significant anti-inflammatory effect. Additionally, the two compounds could be visualised in vitro by confocal microscopy in the submicromolar range. |
| doi_str_mv | 10.1039/c7dt01377a |
| format | Article |
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| ispartof | Dalton transactions : an international journal of inorganic chemistry, 2017, Vol.46 (25), p.8051-8056 |
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| source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Anti-Inflammatory Agents - chemical synthesis Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Anticancer properties Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Antiproliferatives Bimetals Boron Compounds - chemistry Cancer Cell Line, Tumor Cell Proliferation - drug effects Chemical Sciences Colon Confocal Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - pharmacology Drug Discovery Fluorescent Dyes - chemistry Gold - chemistry Humans Imidazoles - chemistry Life Sciences Microscopy Prostate Synthesis |
| title | Gold(i)-BODIPY-imidazole bimetallic complexes as new potential anti-inflammatory and anticancer trackable agents |
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