Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells

Cationic lipid/co-lipid combinations have been extensively explored in gene delivery as alternatives to viral vectors. To be established as a gold standard of chemical vectors, considerable improvement in their transfection efficiency is however required. Herein, we report a simple procedure to synt...

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Veröffentlicht in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2017-09, Vol.5 (33), p.6869-6881
Hauptverfasser: Berchel, Mathieu, Akhter, Sohail, Berthe, Wilfried, Gonçalves, Cristine, Dubuisson, Marine, Pichon, Chantal, Jaffrès, Paul-Alain, Midoux, Patrick
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Sprache:eng
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