In Vivo Occupancy of Dopamine D 3 Receptors by Antagonists Produces Neurochemical and Behavioral Effects of Potential Relevance to Attention-Deficit–Hyperactivity Disorder

Dopamine D-3 receptors have eluded definitive linkage to neurologic and psychiatric disorders since their cloning over 20 years ago. We report a new method that does not employ a radiolabel for simultaneously defining in vivo receptor occupancy of D-3 and D-2 receptors in rat brain after systemic do...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2013-02, Vol.344 (2), p.501-510
Hauptverfasser:	Barth, V., Need, A. B., Tzavara, E. T., Giros, B., Overshiner, C., Gleason, S. D., Wade, M., Johansson, A. M., Perry, K., Nomikos, G. G., Witkin, J. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences Neurons and Cognition
Online-Zugang:	Volltext
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