Do the Side Effects of BRAF Inhibitors Mimic RASopathies?

Recent advances in targeted anticancer therapies have substantially improved the prognosis of several cancers. Such targeted therapies are not, however, free of side effects, and these side effects are clearly distinct from those induced by classical cytotoxic chemotherapies. This is likely so becau...

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Veröffentlicht in:	Journal of investigative dermatology 2017-04, Vol.137 (4), p.805-809
Hauptverfasser:	Sfecci, Alicia, Dupuy, Alain, Dinulescu, Monica, Droitcourt, Catherine, Adamski, Henri, Hadj-Rabia, Smail, Odent, Sylvie, Galibert, Marie-Dominique, Boussemart, Lise
Format:	Artikel
Sprache:	eng
Schlagworte:	Genetics Humans Life Sciences Melanoma - drug therapy Melanoma - genetics Melanoma - pathology Molecular Targeted Therapy - adverse effects Molecular Targeted Therapy - methods Prognosis Protein Kinase Inhibitors - administration & dosage Protein Kinase Inhibitors - adverse effects Proto-Oncogene Proteins B-raf - drug effects Proto-Oncogene Proteins B-raf - genetics Risk Assessment Skin Neoplasms - drug therapy Skin Neoplasms - genetics Skin Neoplasms - pathology Treatment Outcome
Online-Zugang:	Volltext
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