Fully automated production of sodium [18F]fluoride on AllInOne and miniAllInOne synthesizers
A fully automated production of the imaging agent sodium [18F]fluoride ([18F]NaF) on two different modules commercialized by Trasis®, the AllInOne and the miniAllInOne, is reported. Both modules allow to prepare [18F]NaF in good radiochemical yield (around 97%) in less than 4min with the same specif...
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| Veröffentlicht in: | Applied radiation and isotopes 2015-08, Vol.102, p.87-92 |
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| container_title | Applied radiation and isotopes |
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| creator | Collet, Charlotte Otabashi, Muhammad Giacomelli, Fabrice Veran, Nicolas Karcher, Gilles Chapleur, Yves Lamandé-Langle, Sandrine |
| description | A fully automated production of the imaging agent sodium [18F]fluoride ([18F]NaF) on two different modules commercialized by Trasis®, the AllInOne and the miniAllInOne, is reported. Both modules allow to prepare [18F]NaF in good radiochemical yield (around 97%) in less than 4min with the same specifications. Quality control of [18F]NaF produced by this way was performed according to the US and European Pharmacopeia monograph requirements.
•A fully automated production of [18F]NaF on AllInOne and miniAllInOne synthesizers is reported.•Radiochemical yields of 97% in less than 4min were obtained.•Radiochemical purity of more than 99% was achieved. |
| doi_str_mv | 10.1016/j.apradiso.2015.04.016 |
| format | Article |
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•A fully automated production of [18F]NaF on AllInOne and miniAllInOne synthesizers is reported.•Radiochemical yields of 97% in less than 4min were obtained.•Radiochemical purity of more than 99% was achieved.</description><subject>[18F]NaF</subject><subject>Chemical Sciences</subject><subject>Fluorine Radioisotopes - chemistry</subject><subject>Positron emission tomography</subject><subject>Radiopharmaceutical</subject><subject>Sodium [18F]fluoride</subject><subject>Sodium Fluoride - chemical synthesis</subject><issn>0969-8043</issn><issn>1872-9800</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9vGyEQxVHVKHHTfAVrj-1htwPL4uVWK6pjS5ZyaU5JhVj-yFjs4sJuJPfTB8uJrz2BHr-ZN8xDaI6hwoDZj30lD1Fql0JFADcV0CrLn9AMtwtS8hbgM5oBZ7xsgdY36EtKewCgLSfX6IYwAEIWdIZeVpP3x0JOY-jlaHRxiEFPanRhKIItUtBu6otn3K7-WD-F6LQp8tPS-83wOJhCDrro3eAuQjoO484k98_E9BVdWemTuXs_b9HT6tfv-3W5fXzY3C-3paI1H0veECktxR3NYxO90AqDbSmQDjpSK8qt7BregKQLCxRzVksFHa87Wzea5Mst-n7uu5NeHKLrZTyKIJ1YL7fipAGmnAFpXnFmv53Z_NG_k0mj6F1Sxns5mDAlgVnLKGYNhoyyM6piSCkae-mNQZxSEHvxkYI4pSCAZiuWC-fvHlPXG30p-1h7Bn6eAZO38upMFEk5MyijXTRqFDq4_3m8AXdSm18</recordid><startdate>20150801</startdate><enddate>20150801</enddate><creator>Collet, Charlotte</creator><creator>Otabashi, Muhammad</creator><creator>Giacomelli, Fabrice</creator><creator>Veran, Nicolas</creator><creator>Karcher, Gilles</creator><creator>Chapleur, Yves</creator><creator>Lamandé-Langle, Sandrine</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0001-8569-5793</orcidid></search><sort><creationdate>20150801</creationdate><title>Fully automated production of sodium [18F]fluoride on AllInOne and miniAllInOne synthesizers</title><author>Collet, Charlotte ; Otabashi, Muhammad ; Giacomelli, Fabrice ; Veran, Nicolas ; Karcher, Gilles ; Chapleur, Yves ; Lamandé-Langle, Sandrine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-952aaf41b48002d7dc10f8402b0b23c49fab5950a47f041963ac0b93bf35d2b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>[18F]NaF</topic><topic>Chemical Sciences</topic><topic>Fluorine Radioisotopes - chemistry</topic><topic>Positron emission tomography</topic><topic>Radiopharmaceutical</topic><topic>Sodium [18F]fluoride</topic><topic>Sodium Fluoride - chemical synthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Collet, Charlotte</creatorcontrib><creatorcontrib>Otabashi, Muhammad</creatorcontrib><creatorcontrib>Giacomelli, Fabrice</creatorcontrib><creatorcontrib>Veran, Nicolas</creatorcontrib><creatorcontrib>Karcher, Gilles</creatorcontrib><creatorcontrib>Chapleur, Yves</creatorcontrib><creatorcontrib>Lamandé-Langle, Sandrine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Applied radiation and isotopes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Collet, Charlotte</au><au>Otabashi, Muhammad</au><au>Giacomelli, Fabrice</au><au>Veran, Nicolas</au><au>Karcher, Gilles</au><au>Chapleur, Yves</au><au>Lamandé-Langle, Sandrine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fully automated production of sodium [18F]fluoride on AllInOne and miniAllInOne synthesizers</atitle><jtitle>Applied radiation and isotopes</jtitle><addtitle>Appl Radiat Isot</addtitle><date>2015-08-01</date><risdate>2015</risdate><volume>102</volume><spage>87</spage><epage>92</epage><pages>87-92</pages><issn>0969-8043</issn><eissn>1872-9800</eissn><abstract>A fully automated production of the imaging agent sodium [18F]fluoride ([18F]NaF) on two different modules commercialized by Trasis®, the AllInOne and the miniAllInOne, is reported. Both modules allow to prepare [18F]NaF in good radiochemical yield (around 97%) in less than 4min with the same specifications. Quality control of [18F]NaF produced by this way was performed according to the US and European Pharmacopeia monograph requirements.
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| ispartof | Applied radiation and isotopes, 2015-08, Vol.102, p.87-92 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | [18F]NaF Chemical Sciences Fluorine Radioisotopes - chemistry Positron emission tomography Radiopharmaceutical Sodium [18F]fluoride Sodium Fluoride - chemical synthesis |
| title | Fully automated production of sodium [18F]fluoride on AllInOne and miniAllInOne synthesizers |
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