Local and tissue-scale forces drive oriented junction growth during tissue extension

Convergence–extension is a widespread morphogenetic process driven by polarized cell intercalation. In the Drosophila germ band, epithelial intercalation comprises loss of junctions between anterior–posterior neighbours followed by growth of new junctions between dorsal–ventral neighbours. Much is k...

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Veröffentlicht in:	Nature cell biology 2015-10, Vol.17 (10), p.1247-1258
Hauptverfasser:	Collinet, Claudio, Rauzi, Matteo, Lenne, Pierre-François, Lecuit, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	14 14/19 631/136/1660 631/136/334/1582/715 631/80/79/2028 64/24 Animals Animals, Genetically Modified Body Patterning - genetics Cadherins - genetics Cadherins - metabolism Cancer Research Cell Adhesion - genetics Cell Biology Cell development (Biology) Cell Tracking - methods Cellular Biology Developmental Biology Drosophila melanogaster - embryology Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Embryo, Nonmammalian - embryology Embryo, Nonmammalian - metabolism Fluid flow Fluorescence Recovery After Photobleaching Gene Expression Regulation, Developmental Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Intercellular Junctions - metabolism Life Sciences Luminescent Proteins - genetics Luminescent Proteins - metabolism Methods Microscopy, Confocal Observations Red Fluorescent Protein RNA Interference Stem Cells Time-Lapse Imaging Tissue engineering Tissues
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