O$_2$ reduction and O$_2$-induced damage at the active site of FeFe hydrogenase

FeFe hydrogenases are the most efficient H$_2$-producing enzymes. However, inactivation by O$_2$ remains an obstacle that prevents them being used in many biotechnological devices. Here, we combine electrochemistry, site-directed mutagenesis, molecular dynamics and quantum chemical calculations to u...

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Veröffentlicht in:Nature chemistry 2017, Vol.9 (1), p.88-95
Hauptverfasser: Kubas, Adam, Orain, Christophe, de Sancho, David, Saujet, Laure, Sensi, Matteo, Gauquelin, Charles, Meynial Salles, Isabelle, Soucaille, Philippe, Bottin, Hervé, Baffert, Carole, Fourmond, Vincent, Best, Robert, Blumberger, Jochen, Léger, Christophe
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Sprache:eng
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