Resident PW1+ Progenitor Cells Participate in Vascular Remodeling During Pulmonary Arterial Hypertension

RATIONALE:Pulmonary arterial hypertension is characterized by vascular remodeling and neomuscularization. PW1 progenitor cells can differentiate into smooth muscle cells (SMCs) in vitro. OBJECTIVE:To determine the role of pulmonary PW1 progenitor cells in vascular remodeling characteristic of pulmon...

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Veröffentlicht in:Circulation research 2016-03, Vol.118 (5), p.822-833
Hauptverfasser: Dierick, France, Héry, Tiphaine, Hoareau-Coudert, Bénédicte, Mougenot, Nathalie, Monceau, Virginie, Claude, Caroline, Crisan, Mihaela, Besson, Vanessa, Dorfmüller, Peter, Marodon, Gilles, Fadel, Elie, Humbert, Marc, Yaniz-Galende, Elisa, Hulot, Jean-Sébastien, Marazzi, Giovanna, Sassoon, David, Soubrier, Florent, Nadaud, Sophie
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Sprache:eng
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