Follicular Lymphoma B Cells Generate Functional Regulatory T Cells Via ICOS/ICOSL Pathway and Are Inhibited By Intratumoral Tregs

The prognosis of follicular lymphoma (FL) patients is suspected to be influenced by tumor infiltrating regulatory T cells (Tregs). The mechanism of Tregs enrichment in FL and their impact on malignant FL B cells remains to be elucidated. We analyzed 46 fresh lymph node biopsy samples including FL (n...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Blood 2015-12, Vol.126 (23), p.5018-5018
Hauptverfasser:	Olive, Daniel, LE, Suong Khieu, Thibult, marie-Laure, gondois-Rey, Francoise, Granjeaud, Samuel, Fest, Thierry, Imene, Azzaoui, Bouabdallah, Reda, Broussais, Florence, Xerri, Luc, Leroux, Dominique, Caux, Christophe, Caux, Christine
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!