Amplification and pyrosequencing of near-full-length hepatitis C virus for typing and monitoring antiviral resistant strains

Directly acting antiviral drugs have contributed considerable progress to hepatitis C virus (HCV) treatment, but they show variable activity depending on virus genotypes and subtypes. Therefore, accurate genotyping including recombinant form detection is still of major importance, as is the detectio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical microbiology and infection 2016-05, Vol.22 (5), p.460.e1-460.e10
Hauptverfasser:	Trémeaux, P., Caporossi, A., Ramière, C., Santoni, E., Tarbouriech, N., Thélu, M.-A., Fusillier, K., Geneletti, L., François, O., Leroy, V., Burmeister, W.P., André, P., Morand, P., Larrat, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - therapeutic use Biochemistry, Molecular Biology Drug Resistance, Viral Genotype Genotyping Genotyping Techniques - methods Hepacivirus - classification Hepacivirus - genetics Hepacivirus - isolation & purification hepatitis C virus Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - virology Humans Imidazoles - therapeutic use Life Sciences Mutation, Missense next-generation sequencing Nucleic Acid Amplification Techniques recombinant virus resistance-associated variants RNA, Viral - genetics Sequence Analysis, DNA Sofosbuvir - therapeutic use Structural Biology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!