The accuracy of biochemical interactions is ensured by endothermic stepwise kinetics

The discerning behavior of living systems relies on accurate interactions selected from the lot of molecular collisions occurring in the cell. To ensure the reliability of interactions, binding partners are classically envisioned as finely preadapted molecules, selected on the basis of their affinit...

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Veröffentlicht in:	Progress in biophysics and molecular biology 2016-05, Vol.121 (1), p.35-44
Hauptverfasser:	Michel, Denis, Boutin, Benjamin, Ruelle, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding specificity Biochemistry Cells - metabolism Fluctuation ratchet Induced fit Kinetics Life Sciences Self-assembly Substrate selection Thermodynamics
Online-Zugang:	Volltext
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