Reduced impact of emotion on choice behavior in presymptomatic BACHD rats, a transgenic rodent model for Huntington Disease

•Altered choice efficiency in old BACHD rats (18months).•Emotional state affects exploratory activity and choice behavior in WT animals.•Reduced impact of emotional modulation in BACHD rats from presymptomatic age.•BACHD rats are a good model of executive and emotional dysfunction in HD. Executive d...

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Veröffentlicht in:	Neurobiology of learning and memory 2015-11, Vol.125, p.249-257
Hauptverfasser:	Adjeroud, Najia, Yagüe, Sara, Yu-Taeger, Libo, Bozon, Bruno, Leblanc-Veyrac, Pascale, Riess, Olaf, Allain, Philippe, Nguyen, Huu Phuc, Doyère, Valérie, El Massioui, Nicole
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BACHD transgenic rats Behavior, Animal - physiology Choice Behavior - physiology Cognitive Sciences Disease Models, Animal Electroshock Emotional modulation Emotions - physiology Gambling task Huntington disease Huntington Disease - genetics Huntington Disease - psychology Life Sciences Motor Activity - physiology Neurobiology Neurons and Cognition Psychology and behavior Rats Rats, Transgenic
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