Differential expression of interleukin-17 and interleukin-22 in inflamed and non-inflamed synovium from osteoarthritis patients

Summary Objective Synovitis associated with osteoarthritis (OA) is directly responsible for several clinical symptoms and reflects OA's structural progression. This study sought to analyze the expression of proinflammatory mediations, including Interleukin (IL)-17 and IL-22, which play key role...

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Veröffentlicht in:	Osteoarthritis and cartilage 2015-11, Vol.23 (11), p.1843-1852
Hauptverfasser:	Deligne, C, Casulli, S, Pigenet, A, Bougault, C, Campillo-Gimenez, L, Nourissat, G, Berenbaum, F, Elbim, C, Houard, X
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Enzyme-Linked Immunosorbent Assay Female Gene Expression Regulation Human health and pathology Humans IL-17 IL-22 Immunohistochemistry Interleukin-17 - biosynthesis Interleukin-17 - genetics Interleukin-22 Interleukins - biosynthesis Interleukins - genetics Life Sciences Male Middle Aged Osteoarthritis Osteoarthritis, Knee - complications Osteoarthritis, Knee - genetics Osteoarthritis, Knee - metabolism Real-Time Polymerase Chain Reaction Rheumatology Rhumatology and musculoskeletal system RNA - genetics Synovial inflammation Synovial Membrane - metabolism Synovitis - etiology Synovitis - genetics Synovitis - metabolism
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