Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis

The spatial orientation of cell divisions is fundamental for tissue architecture and homeostasis. Here we analysed neuroepithelial progenitors in the developing mouse spinal cord to determine whether extracellular signals orient the mitotic spindle. We report that Semaphorin3B (Sema3B) released from...

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Veröffentlicht in:	Nature communications 2015-02, Vol.6 (1), p.6366-6366, Article 6366
Hauptverfasser:	Arbeille, Elise, Reynaud, Florie, Sanyas, Isabelle, Bozon, Muriel, Kindbeiter, Karine, Causeret, Frédéric, Pierani, Alessandra, Falk, Julien, Moret, Frédéric, Castellani, Valérie
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 13/109 13/44 13/51 14 14/1 14/19 14/34 38/35 38/71 631/378/368/2430 631/45/612/1224 631/80/641 631/80/85/2361 64/110 64/60 82/29 Animals Blotting, Western Cell Division - physiology Cell Polarity - physiology Fluorescent Antibody Technique HeLa Cells Humanities and Social Sciences Humans In Situ Hybridization Intercellular Signaling Peptides and Proteins - metabolism Life Sciences Mice Mice, Knockout multidisciplinary Nerve Tissue Proteins - metabolism Neuroepithelial Cells - physiology Neurons and Cognition Neuropilins - metabolism Science Science (multidisciplinary) Semaphorins - cerebrospinal fluid Semaphorins - metabolism Spinal Cord - cytology Spinal Cord - embryology Statistics, Nonparametric
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