Detection of Drug–Drug Interactions Inducing Acute Kidney Injury by Electronic Health Records Mining

Background and Objective While risk of acute kidney injury (AKI) is a well documented adverse effect of some drugs, few studies have assessed the relationship between drug–drug interactions (DDIs) and AKI. Our objective was to develop an algorithm capable of detecting potential signals on this relat...

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Veröffentlicht in:	Drug safety 2015-09, Vol.38 (9), p.799-809
Hauptverfasser:	Girardeau, Yannick, Trivin, Claire, Durieux, Pierre, Le Beller, Christine, Louet Agnes, Lillo-Le, Neuraz, Antoine, Degoulet, Patrice, Avillach, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - chemically induced Adult Aged Aged, 80 and over Algorithms Data mining Data Mining - methods Drug Interactions Drug Safety and Pharmacovigilance Electronic health records Electronic Health Records - statistics & numerical data Female Funding Hospitalization Human health and pathology Humans Life Sciences Male Medicine Medicine & Public Health Middle Aged Mortality Original Research Article Pharmaceutical sciences Pharmacology/Toxicology Retrospective Studies Sensitivity and Specificity Studies Urology and Nephrology
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