An adhesome comprising laminin, dystroglycan and myosin IIA is required during notochord development in Xenopus laevis

Dystroglycan (Dg) is a transmembrane receptor for laminin that must be expressed at the right time and place in order to be involved in notochord morphogenesis. The function of Dg was examined in Xenopus laevis embryos by knockdown of Dg and overexpression and replacement of the endogenous Dg with a...

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Veröffentlicht in:	Development (Cambridge) 2014-12, Vol.141 (23), p.4569-4579
Hauptverfasser:	Buisson, Nicolas, Sirour, Cathy, Moreau, Nicole, Denker, Elsa, Le Bouffant, Ronan, Goullancourt, Aline, Darribère, Thierry, Bello, Valérie
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Bromodeoxyuridine Cell Polarity - physiology Development Biology Dystroglycans - metabolism Gene Knockdown Techniques Immunoprecipitation In Situ Hybridization Laminin - metabolism Life Sciences Morpholinos - genetics Nonmuscle Myosin Type IIA - metabolism Notochord - embryology Organogenesis - physiology Proteomics Tandem Mass Spectrometry Vacuoles - physiology Xenopus laevis Xenopus laevis - embryology
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