Haematological parameters do senesce in the wild: evidence from different populations of a long‐lived mammal
Increasing evidence of senescence has been reported from long‐term studies of wild populations. However, most studies have focused on life‐history traits like survival, reproduction or body mass, generally from a single intensively monitored population. However, variation in the intensity of senesce...
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creator | Jégo, M Lemaître, J.‐F Bourgoin, G Capron, G Warnant, C Klein, F Gilot‐Fromont, E Gaillard, J‐M |
description | Increasing evidence of senescence has been reported from long‐term studies of wild populations. However, most studies have focused on life‐history traits like survival, reproduction or body mass, generally from a single intensively monitored population. However, variation in the intensity of senescence across populations, and to a lesser extent between sexes, is still poorly understood. In addition, the pattern of age‐specific changes in haematological parameters remains virtually unknown to date for any population of vertebrate living in the wild. Using repeated blood samples collected from known‐aged (2–15 years of age) roe deer (Capreolus capreolus) from two populations facing highly different environmental conditions, we filled the gap. In particular, we investigated age‐specific changes in haematocrit, albumin and creatinine. We reported clear evidence of senescence in all haematological parameters. Moreover, senescence patterns differed between sexes and populations. The rate of senescence was higher in males than in females for haematocrit with no site difference. On the other hand, the rate of senescence in creatinine was higher at Trois Fontaines than at Chizé with no sex difference. Our findings provide a first demonstration of age‐specific declines in haematological parameters in wild populations of large herbivores and show that the process of senescence in vertebrates is not restricted to body mass or fitness components. We also demonstrate that the senescence pattern of haematological parameters is context dependent and varies both between sexes and according to environmental conditions. |
doi_str_mv | 10.1111/jeb.12535 |
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However, most studies have focused on life‐history traits like survival, reproduction or body mass, generally from a single intensively monitored population. However, variation in the intensity of senescence across populations, and to a lesser extent between sexes, is still poorly understood. In addition, the pattern of age‐specific changes in haematological parameters remains virtually unknown to date for any population of vertebrate living in the wild. Using repeated blood samples collected from known‐aged (2–15 years of age) roe deer (Capreolus capreolus) from two populations facing highly different environmental conditions, we filled the gap. In particular, we investigated age‐specific changes in haematocrit, albumin and creatinine. We reported clear evidence of senescence in all haematological parameters. Moreover, senescence patterns differed between sexes and populations. The rate of senescence was higher in males than in females for haematocrit with no site difference. On the other hand, the rate of senescence in creatinine was higher at Trois Fontaines than at Chizé with no sex difference. Our findings provide a first demonstration of age‐specific declines in haematological parameters in wild populations of large herbivores and show that the process of senescence in vertebrates is not restricted to body mass or fitness components. We also demonstrate that the senescence pattern of haematological parameters is context dependent and varies both between sexes and according to environmental conditions.</description><identifier>ISSN: 1010-061X</identifier><identifier>EISSN: 1420-9101</identifier><identifier>DOI: 10.1111/jeb.12535</identifier><identifier>PMID: 25358546</identifier><language>eng</language><publisher>Switzerland: Birkhäuser</publisher><subject>Age Factors ; ageing ; Aging - blood ; Aging - physiology ; albumin ; albumins ; Animal populations ; Animals ; Animals, Wild - blood ; Animals, Wild - physiology ; blood ; Capreolus capreolus ; creatinine ; Creatinine - blood ; Deer - blood ; Deer - physiology ; Environment ; Environmental conditions ; environmental factors ; Evolution ; Female ; females ; France ; Geography ; haematocrit ; Hematocrit ; Hematology ; herbivores ; life history ; Life Sciences ; Male ; males ; Mammals ; Models, Biological ; reproduction ; roe deer ; Senescence ; Sex Factors ; vertebrate</subject><ispartof>Journal of evolutionary biology, 2014-12, Vol.27 (12), p.2745-2752</ispartof><rights>2014 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology</rights><rights>2014 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.</rights><rights>Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4795-72d372d5fea6e27c63020dc084b5a1afe91e437403541fa82aa5ebcf61f5cf003</citedby><cites>FETCH-LOGICAL-c4795-72d372d5fea6e27c63020dc084b5a1afe91e437403541fa82aa5ebcf61f5cf003</cites><orcidid>0000-0003-0993-0741 ; 0000-0001-9898-2353 ; 0000-0003-0011-7519 ; 0000-0003-0174-8451</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjeb.12535$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjeb.12535$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25358546$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-01140487$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Jégo, M</creatorcontrib><creatorcontrib>Lemaître, J.‐F</creatorcontrib><creatorcontrib>Bourgoin, G</creatorcontrib><creatorcontrib>Capron, G</creatorcontrib><creatorcontrib>Warnant, C</creatorcontrib><creatorcontrib>Klein, F</creatorcontrib><creatorcontrib>Gilot‐Fromont, E</creatorcontrib><creatorcontrib>Gaillard, J‐M</creatorcontrib><title>Haematological parameters do senesce in the wild: evidence from different populations of a long‐lived mammal</title><title>Journal of evolutionary biology</title><addtitle>J Evol Biol</addtitle><description>Increasing evidence of senescence has been reported from long‐term studies of wild populations. However, most studies have focused on life‐history traits like survival, reproduction or body mass, generally from a single intensively monitored population. However, variation in the intensity of senescence across populations, and to a lesser extent between sexes, is still poorly understood. In addition, the pattern of age‐specific changes in haematological parameters remains virtually unknown to date for any population of vertebrate living in the wild. Using repeated blood samples collected from known‐aged (2–15 years of age) roe deer (Capreolus capreolus) from two populations facing highly different environmental conditions, we filled the gap. In particular, we investigated age‐specific changes in haematocrit, albumin and creatinine. We reported clear evidence of senescence in all haematological parameters. Moreover, senescence patterns differed between sexes and populations. The rate of senescence was higher in males than in females for haematocrit with no site difference. On the other hand, the rate of senescence in creatinine was higher at Trois Fontaines than at Chizé with no sex difference. Our findings provide a first demonstration of age‐specific declines in haematological parameters in wild populations of large herbivores and show that the process of senescence in vertebrates is not restricted to body mass or fitness components. We also demonstrate that the senescence pattern of haematological parameters is context dependent and varies both between sexes and according to environmental conditions.</description><subject>Age Factors</subject><subject>ageing</subject><subject>Aging - blood</subject><subject>Aging - physiology</subject><subject>albumin</subject><subject>albumins</subject><subject>Animal populations</subject><subject>Animals</subject><subject>Animals, Wild - blood</subject><subject>Animals, Wild - physiology</subject><subject>blood</subject><subject>Capreolus capreolus</subject><subject>creatinine</subject><subject>Creatinine - blood</subject><subject>Deer - blood</subject><subject>Deer - physiology</subject><subject>Environment</subject><subject>Environmental conditions</subject><subject>environmental factors</subject><subject>Evolution</subject><subject>Female</subject><subject>females</subject><subject>France</subject><subject>Geography</subject><subject>haematocrit</subject><subject>Hematocrit</subject><subject>Hematology</subject><subject>herbivores</subject><subject>life history</subject><subject>Life Sciences</subject><subject>Male</subject><subject>males</subject><subject>Mammals</subject><subject>Models, Biological</subject><subject>reproduction</subject><subject>roe deer</subject><subject>Senescence</subject><subject>Sex Factors</subject><subject>vertebrate</subject><issn>1010-061X</issn><issn>1420-9101</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksGKFDEQhoMo7jp68AU04EUPvVvpJN093tZldZQBD7rgLdR0V2YzpDtt0jOyNx_BZ_RJzDi7KwiCgZBQfPVTVX8x9lTAicjndEOrE1Fqqe-xY6FKKOYCxP38BwEFVOLLEXuU0gZAVErrh-xozzZaVcdsWCD1OAUf1q5Fz0eM2NNEMfEu8EQDpZa4G_h0Rfyb891rTjvX0ZCjNoaed85aijRMfAzj1uPkwpB4sBy5D8P65_cf3u2o4z32PfrH7IFFn-jJzTtjl28vPp8viuXHd-_Pz5ZFq-q5Luqyk_lqS1hRWbeVhBK6Fhq10ijQ0lyQkrUCqZWw2JSImlatrYTVrQWQM_bqoHuF3ozR9RivTUBnFmdLs4-BEApUU-9EZl8e2DGGr1tKk-ldbtp7HChsk8lDq6EUINV_oLLWWqs83xl78Re6Cds45Kb3lJayrJvmT51tDClFsnfFCjB7b0321vz2NrPPbhS3q566O_LWzAycHoDsE13_W8l8uHhzK_n8kGExGFxHl8zlpxKEzqvSKCVK-QvTpbYq</recordid><startdate>201412</startdate><enddate>201412</enddate><creator>Jégo, M</creator><creator>Lemaître, J.‐F</creator><creator>Bourgoin, G</creator><creator>Capron, G</creator><creator>Warnant, C</creator><creator>Klein, F</creator><creator>Gilot‐Fromont, E</creator><creator>Gaillard, J‐M</creator><general>Birkhäuser</general><general>Blackwell Publishing Ltd</general><general>Wiley</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QP</scope><scope>7QR</scope><scope>7SN</scope><scope>7SS</scope><scope>7TK</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0003-0993-0741</orcidid><orcidid>https://orcid.org/0000-0001-9898-2353</orcidid><orcidid>https://orcid.org/0000-0003-0011-7519</orcidid><orcidid>https://orcid.org/0000-0003-0174-8451</orcidid></search><sort><creationdate>201412</creationdate><title>Haematological parameters do senesce in the wild: evidence from different populations of a long‐lived mammal</title><author>Jégo, M ; 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However, most studies have focused on life‐history traits like survival, reproduction or body mass, generally from a single intensively monitored population. However, variation in the intensity of senescence across populations, and to a lesser extent between sexes, is still poorly understood. In addition, the pattern of age‐specific changes in haematological parameters remains virtually unknown to date for any population of vertebrate living in the wild. Using repeated blood samples collected from known‐aged (2–15 years of age) roe deer (Capreolus capreolus) from two populations facing highly different environmental conditions, we filled the gap. In particular, we investigated age‐specific changes in haematocrit, albumin and creatinine. We reported clear evidence of senescence in all haematological parameters. Moreover, senescence patterns differed between sexes and populations. The rate of senescence was higher in males than in females for haematocrit with no site difference. On the other hand, the rate of senescence in creatinine was higher at Trois Fontaines than at Chizé with no sex difference. Our findings provide a first demonstration of age‐specific declines in haematological parameters in wild populations of large herbivores and show that the process of senescence in vertebrates is not restricted to body mass or fitness components. We also demonstrate that the senescence pattern of haematological parameters is context dependent and varies both between sexes and according to environmental conditions.</abstract><cop>Switzerland</cop><pub>Birkhäuser</pub><pmid>25358546</pmid><doi>10.1111/jeb.12535</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0993-0741</orcidid><orcidid>https://orcid.org/0000-0001-9898-2353</orcidid><orcidid>https://orcid.org/0000-0003-0011-7519</orcidid><orcidid>https://orcid.org/0000-0003-0174-8451</orcidid><oa>free_for_read</oa></addata></record> |
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source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Age Factors ageing Aging - blood Aging - physiology albumin albumins Animal populations Animals Animals, Wild - blood Animals, Wild - physiology blood Capreolus capreolus creatinine Creatinine - blood Deer - blood Deer - physiology Environment Environmental conditions environmental factors Evolution Female females France Geography haematocrit Hematocrit Hematology herbivores life history Life Sciences Male males Mammals Models, Biological reproduction roe deer Senescence Sex Factors vertebrate |
title | Haematological parameters do senesce in the wild: evidence from different populations of a long‐lived mammal |
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