Reconstitution of Natural Killer Cells in HLA-Matched HSCT after Reduced-Intensity Conditioning: Impact on Clinical Outcome

Abstract Recent advances in the development of reduced-intensity conditioning (RIC) have allowed a broader range of patients to access allogeneic hematopoietic stem cell transplantation (HSCT). Reconstitution of an effective immune system post-transplant, including natural killer (NK) cells, is crit...

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Veröffentlicht in:	Biology of blood and marrow transplantation 2015-03, Vol.21 (3), p.429-439
Hauptverfasser:	Pical-Izard, Caroline, Crocchiolo, Roberto, Granjeaud, Samuel, Kochbati, Eloise, Just-Landi, Sylvaine, Chabannon, Christian, Frassati, Coralie, Picard, Christophe, Blaise, Didier, Olive, Daniel, Fauriat, Cyril
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Allografts Cytokines - immunology Disease-Free Survival Female Follow-Up Studies Hematologic Neoplasms - immunology Hematologic Neoplasms - mortality Hematologic Neoplasms - therapy Hematology Hematology, Oncology and Palliative Medicine Hematopoietic Stem Cell Transplantation Histocompatibility Testing HLA-matched Human health and pathology Humans Killer Cells, Natural - immunology Life Sciences Male Middle Aged NK cells NK functions Recovery of Function - immunology Reduced-intensity conditioning Stem cell transplantation Survival Rate Transplantation Conditioning Unrelated Donors
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