Classification of axial SpA based on positive imaging (radiographs and/or MRI of the sacroiliac joints) by local rheumatologists or radiologists versus central trained readers in the DESIR cohort
ObjectiveInvestigating changes in patient classification (ASAS (Assessment of SpondyloArthritis international Society) axSpA criteria) based on evaluation of images of the sacro-iliac joints (MRI-SI and X-SI) by local and central readers.MethodsThe DESIR cohort included patients with inflammatory ba...
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Veröffentlicht in: | Annals of the rheumatic diseases 2015-11, Vol.74 (11), p.2016-2021 |
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creator | van den Berg, Rosaline Lenczner, Grégory Thévenin, Fabrice Claudepierre, Pascal Feydy, Antoine Reijnierse, Monique Saraux, Alain Rahmouni, Alain Dougados, Maxime van der Heijde, Désirée |
description | ObjectiveInvestigating changes in patient classification (ASAS (Assessment of SpondyloArthritis international Society) axSpA criteria) based on evaluation of images of the sacro-iliac joints (MRI-SI and X-SI) by local and central readers.MethodsThe DESIR cohort included patients with inflammatory back pain (IBP; ≥3 months, but |
doi_str_mv | 10.1136/annrheumdis-2014-205432 |
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fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_01030844v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1808617707</sourcerecordid><originalsourceid>FETCH-LOGICAL-b451t-f5bd85647af8b3895aa6883a37c9a264742d92357bcd191c1a9490a881396f333</originalsourceid><addsrcrecordid>eNqNksFu1DAQhiMEokvhFcASl_YQasdO7BxXS6ErLUJq4RxNEmfjVWIvtrOiz8eLMbtpK8QFLmPN-JvfY_tPkneMfmCMF1dgre_1NLYmpBllAkMuePYsWTBRKMwK-jxZUEp5KspCniWvQthhShVTL5OzDIuZkmyR_FoNEILpTAPROEtcR-CngYHc7ZekhqBbgtW9CyaagyZmhK2xW3LhoTVu62HfBwK2vXKefLldH9tjr0mAxjszGGjIzhkbwyWp78ngGhQ-zQ3RDW5rQgwEO09ij_lB-zAF0mgbPeIYjMUpvIYWd4ixpxM-Xt-tb0njeufj6-RFB0PQbx7W8-T7p-tvq5t08_XzerXcpLXIWUy7vG5VXggJnaq5KnOAQikOXDYlZFgXWVtmPJd107KSNQxKUVJQivGy6Djn58nlrNvDUO09voW_rxyY6ma5qY41yiinSogDQ_ZiZvfe_Zh0iNVoQqOHAax2U6iYoqpgUlL5b1RmjItCZAWi7_9Cd27yFi-NlJRKoGiJlJwp_IQQvO6ehmW0Otqn-sM-1dE-1Wwf7Hz7oD_Vo26f-h79gkA2A_W4-2_V3xES1Wc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1777840869</pqid></control><display><type>article</type><title>Classification of axial SpA based on positive imaging (radiographs and/or MRI of the sacroiliac joints) by local rheumatologists or radiologists versus central trained readers in the DESIR cohort</title><source>MEDLINE</source><source>BMJ Journals - NESLi2</source><creator>van den Berg, Rosaline ; Lenczner, Grégory ; Thévenin, Fabrice ; Claudepierre, Pascal ; Feydy, Antoine ; Reijnierse, Monique ; Saraux, Alain ; Rahmouni, Alain ; Dougados, Maxime ; van der Heijde, Désirée</creator><creatorcontrib>van den Berg, Rosaline ; Lenczner, Grégory ; Thévenin, Fabrice ; Claudepierre, Pascal ; Feydy, Antoine ; Reijnierse, Monique ; Saraux, Alain ; Rahmouni, Alain ; Dougados, Maxime ; van der Heijde, Désirée</creatorcontrib><description>ObjectiveInvestigating changes in patient classification (ASAS (Assessment of SpondyloArthritis international Society) axSpA criteria) based on evaluation of images of the sacro-iliac joints (MRI-SI and X-SI) by local and central readers.MethodsThe DESIR cohort included patients with inflammatory back pain (IBP; ≥3 months, but <3 years), suggestive of axSpA. Local radiologists/rheumatologists (local-reading) and two central readers (central-reading) evaluated baseline images. Agreement regarding positive MRI (pos-MRI) between central readers and between local-reading and central-reading was calculated (κs). Number of patients classified differently (ASAS criteria) by using local-reading instead of central-reading was calculated.ResultsInter-reader agreement between the two central readers and between local-reading and central-reading was substantial (κ=0.73 and κ=0.70, respectively). In 89/663 MRI-SIs (13.4%) local-reading and central-reading disagreed; 38/223 patients (17.0%) with pos-MRI (local-reading) were negative by central-reading; 51/440 patients (11.6%) with neg-MRI (local-reading) were positive by central-reading.In 163/582 patients eligible for applying ASAS criteria (28.0%), local-reading and central-reading disagreed on positive imaging (MRI-SI and/or X-SI; κ=0.68). In 46/582 patients (7.9%) a different evaluation resulted in a different classification; 18/582 patients (3.1%) classified no-SpA (central-reading) were axSpA by local-reading; 28/582 patients (4.8%) classified axSpA (central-reading) were no-SpA by local-reading. Among axSpA patients (central-reading), 16/419 patients (3.8%) fulfilling imaging-arm by central-reading fulfilled clinical-arm by local-reading; 29/419 patients (6.9%) fulfilling clinical-arm by central-reading fulfilled also imaging-arm by local-reading.ConclusionsIn patients with recent onset IBP, trained readers and local rheumatologists/radiologists agree well on recognising a pos-MRI. While disagreeing in 28% of the patients on positive imaging (MRI-SI and/or X-SI), classification of only 7.9% of the patients changed based on a different evaluation of images, showing the ASAS axSpA criteria's robustness.</description><identifier>ISSN: 0003-4967</identifier><identifier>EISSN: 1468-2060</identifier><identifier>DOI: 10.1136/annrheumdis-2014-205432</identifier><identifier>PMID: 24962871</identifier><identifier>CODEN: ARDIAO</identifier><language>eng</language><publisher>England: Elsevier Limited</publisher><subject>Adolescent ; Adult ; Agreements ; Back pain ; Back Pain - etiology ; Back Pain - pathology ; Classification ; Clinical medicine ; Clinical trials ; Cohort Studies ; Edema ; Female ; Humans ; Laboratories ; Life Sciences ; Longitudinal Studies ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Observer Variation ; Patients ; Prospective Studies ; Radiology - standards ; Reading ; Rheumatology - standards ; Sacroiliac Joint - pathology ; Sacroiliitis - complications ; Sacroiliitis - pathology ; Severity of Illness Index ; Spondylarthropathies - complications ; Spondylarthropathies - pathology ; Spondylitis, Ankylosing - complications ; Spondylitis, Ankylosing - pathology ; Young Adult</subject><ispartof>Annals of the rheumatic diseases, 2015-11, Vol.74 (11), p.2016-2021</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>Copyright: 2015 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b451t-f5bd85647af8b3895aa6883a37c9a264742d92357bcd191c1a9490a881396f333</citedby><cites>FETCH-LOGICAL-b451t-f5bd85647af8b3895aa6883a37c9a264742d92357bcd191c1a9490a881396f333</cites><orcidid>0000-0002-8454-7067 ; 0000-0002-5781-158X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://ard.bmj.com/content/74/11/2016.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://ard.bmj.com/content/74/11/2016.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,776,780,881,3183,23550,27901,27902,77342,77373</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24962871$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.univ-brest.fr/hal-01030844$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>van den Berg, Rosaline</creatorcontrib><creatorcontrib>Lenczner, Grégory</creatorcontrib><creatorcontrib>Thévenin, Fabrice</creatorcontrib><creatorcontrib>Claudepierre, Pascal</creatorcontrib><creatorcontrib>Feydy, Antoine</creatorcontrib><creatorcontrib>Reijnierse, Monique</creatorcontrib><creatorcontrib>Saraux, Alain</creatorcontrib><creatorcontrib>Rahmouni, Alain</creatorcontrib><creatorcontrib>Dougados, Maxime</creatorcontrib><creatorcontrib>van der Heijde, Désirée</creatorcontrib><title>Classification of axial SpA based on positive imaging (radiographs and/or MRI of the sacroiliac joints) by local rheumatologists or radiologists versus central trained readers in the DESIR cohort</title><title>Annals of the rheumatic diseases</title><addtitle>Ann Rheum Dis</addtitle><description>ObjectiveInvestigating changes in patient classification (ASAS (Assessment of SpondyloArthritis international Society) axSpA criteria) based on evaluation of images of the sacro-iliac joints (MRI-SI and X-SI) by local and central readers.MethodsThe DESIR cohort included patients with inflammatory back pain (IBP; ≥3 months, but <3 years), suggestive of axSpA. Local radiologists/rheumatologists (local-reading) and two central readers (central-reading) evaluated baseline images. Agreement regarding positive MRI (pos-MRI) between central readers and between local-reading and central-reading was calculated (κs). Number of patients classified differently (ASAS criteria) by using local-reading instead of central-reading was calculated.ResultsInter-reader agreement between the two central readers and between local-reading and central-reading was substantial (κ=0.73 and κ=0.70, respectively). In 89/663 MRI-SIs (13.4%) local-reading and central-reading disagreed; 38/223 patients (17.0%) with pos-MRI (local-reading) were negative by central-reading; 51/440 patients (11.6%) with neg-MRI (local-reading) were positive by central-reading.In 163/582 patients eligible for applying ASAS criteria (28.0%), local-reading and central-reading disagreed on positive imaging (MRI-SI and/or X-SI; κ=0.68). In 46/582 patients (7.9%) a different evaluation resulted in a different classification; 18/582 patients (3.1%) classified no-SpA (central-reading) were axSpA by local-reading; 28/582 patients (4.8%) classified axSpA (central-reading) were no-SpA by local-reading. Among axSpA patients (central-reading), 16/419 patients (3.8%) fulfilling imaging-arm by central-reading fulfilled clinical-arm by local-reading; 29/419 patients (6.9%) fulfilling clinical-arm by central-reading fulfilled also imaging-arm by local-reading.ConclusionsIn patients with recent onset IBP, trained readers and local rheumatologists/radiologists agree well on recognising a pos-MRI. While disagreeing in 28% of the patients on positive imaging (MRI-SI and/or X-SI), classification of only 7.9% of the patients changed based on a different evaluation of images, showing the ASAS axSpA criteria's robustness.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Agreements</subject><subject>Back pain</subject><subject>Back Pain - etiology</subject><subject>Back Pain - pathology</subject><subject>Classification</subject><subject>Clinical medicine</subject><subject>Clinical trials</subject><subject>Cohort Studies</subject><subject>Edema</subject><subject>Female</subject><subject>Humans</subject><subject>Laboratories</subject><subject>Life Sciences</subject><subject>Longitudinal Studies</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Observer Variation</subject><subject>Patients</subject><subject>Prospective Studies</subject><subject>Radiology - standards</subject><subject>Reading</subject><subject>Rheumatology - standards</subject><subject>Sacroiliac Joint - pathology</subject><subject>Sacroiliitis - complications</subject><subject>Sacroiliitis - pathology</subject><subject>Severity of Illness Index</subject><subject>Spondylarthropathies - complications</subject><subject>Spondylarthropathies - pathology</subject><subject>Spondylitis, Ankylosing - complications</subject><subject>Spondylitis, Ankylosing - pathology</subject><subject>Young Adult</subject><issn>0003-4967</issn><issn>1468-2060</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNksFu1DAQhiMEokvhFcASl_YQasdO7BxXS6ErLUJq4RxNEmfjVWIvtrOiz8eLMbtpK8QFLmPN-JvfY_tPkneMfmCMF1dgre_1NLYmpBllAkMuePYsWTBRKMwK-jxZUEp5KspCniWvQthhShVTL5OzDIuZkmyR_FoNEILpTAPROEtcR-CngYHc7ZekhqBbgtW9CyaagyZmhK2xW3LhoTVu62HfBwK2vXKefLldH9tjr0mAxjszGGjIzhkbwyWp78ngGhQ-zQ3RDW5rQgwEO09ij_lB-zAF0mgbPeIYjMUpvIYWd4ixpxM-Xt-tb0njeufj6-RFB0PQbx7W8-T7p-tvq5t08_XzerXcpLXIWUy7vG5VXggJnaq5KnOAQikOXDYlZFgXWVtmPJd107KSNQxKUVJQivGy6Djn58nlrNvDUO09voW_rxyY6ma5qY41yiinSogDQ_ZiZvfe_Zh0iNVoQqOHAax2U6iYoqpgUlL5b1RmjItCZAWi7_9Cd27yFi-NlJRKoGiJlJwp_IQQvO6ehmW0Otqn-sM-1dE-1Wwf7Hz7oD_Vo26f-h79gkA2A_W4-2_V3xES1Wc</recordid><startdate>20151101</startdate><enddate>20151101</enddate><creator>van den Berg, Rosaline</creator><creator>Lenczner, Grégory</creator><creator>Thévenin, Fabrice</creator><creator>Claudepierre, Pascal</creator><creator>Feydy, Antoine</creator><creator>Reijnierse, Monique</creator><creator>Saraux, Alain</creator><creator>Rahmouni, Alain</creator><creator>Dougados, Maxime</creator><creator>van der Heijde, Désirée</creator><general>Elsevier Limited</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>7T5</scope><scope>7TS</scope><scope>H94</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0002-8454-7067</orcidid><orcidid>https://orcid.org/0000-0002-5781-158X</orcidid></search><sort><creationdate>20151101</creationdate><title>Classification of axial SpA based on positive imaging (radiographs and/or MRI of the sacroiliac joints) by local rheumatologists or radiologists versus central trained readers in the DESIR cohort</title><author>van den Berg, Rosaline ; Lenczner, Grégory ; Thévenin, Fabrice ; Claudepierre, Pascal ; Feydy, Antoine ; Reijnierse, Monique ; Saraux, Alain ; Rahmouni, Alain ; Dougados, Maxime ; van der Heijde, Désirée</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b451t-f5bd85647af8b3895aa6883a37c9a264742d92357bcd191c1a9490a881396f333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Agreements</topic><topic>Back pain</topic><topic>Back Pain - etiology</topic><topic>Back Pain - pathology</topic><topic>Classification</topic><topic>Clinical medicine</topic><topic>Clinical trials</topic><topic>Cohort Studies</topic><topic>Edema</topic><topic>Female</topic><topic>Humans</topic><topic>Laboratories</topic><topic>Life Sciences</topic><topic>Longitudinal Studies</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Observer Variation</topic><topic>Patients</topic><topic>Prospective Studies</topic><topic>Radiology - standards</topic><topic>Reading</topic><topic>Rheumatology - standards</topic><topic>Sacroiliac Joint - pathology</topic><topic>Sacroiliitis - complications</topic><topic>Sacroiliitis - pathology</topic><topic>Severity of Illness Index</topic><topic>Spondylarthropathies - complications</topic><topic>Spondylarthropathies - pathology</topic><topic>Spondylitis, Ankylosing - complications</topic><topic>Spondylitis, Ankylosing - pathology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van den Berg, Rosaline</creatorcontrib><creatorcontrib>Lenczner, Grégory</creatorcontrib><creatorcontrib>Thévenin, Fabrice</creatorcontrib><creatorcontrib>Claudepierre, Pascal</creatorcontrib><creatorcontrib>Feydy, Antoine</creatorcontrib><creatorcontrib>Reijnierse, Monique</creatorcontrib><creatorcontrib>Saraux, Alain</creatorcontrib><creatorcontrib>Rahmouni, Alain</creatorcontrib><creatorcontrib>Dougados, Maxime</creatorcontrib><creatorcontrib>van der Heijde, Désirée</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>Physical Education Index</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Annals of the rheumatic diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van den Berg, Rosaline</au><au>Lenczner, Grégory</au><au>Thévenin, Fabrice</au><au>Claudepierre, Pascal</au><au>Feydy, Antoine</au><au>Reijnierse, Monique</au><au>Saraux, Alain</au><au>Rahmouni, Alain</au><au>Dougados, Maxime</au><au>van der Heijde, Désirée</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Classification of axial SpA based on positive imaging (radiographs and/or MRI of the sacroiliac joints) by local rheumatologists or radiologists versus central trained readers in the DESIR cohort</atitle><jtitle>Annals of the rheumatic diseases</jtitle><addtitle>Ann Rheum Dis</addtitle><date>2015-11-01</date><risdate>2015</risdate><volume>74</volume><issue>11</issue><spage>2016</spage><epage>2021</epage><pages>2016-2021</pages><issn>0003-4967</issn><eissn>1468-2060</eissn><coden>ARDIAO</coden><abstract>ObjectiveInvestigating changes in patient classification (ASAS (Assessment of SpondyloArthritis international Society) axSpA criteria) based on evaluation of images of the sacro-iliac joints (MRI-SI and X-SI) by local and central readers.MethodsThe DESIR cohort included patients with inflammatory back pain (IBP; ≥3 months, but <3 years), suggestive of axSpA. Local radiologists/rheumatologists (local-reading) and two central readers (central-reading) evaluated baseline images. Agreement regarding positive MRI (pos-MRI) between central readers and between local-reading and central-reading was calculated (κs). Number of patients classified differently (ASAS criteria) by using local-reading instead of central-reading was calculated.ResultsInter-reader agreement between the two central readers and between local-reading and central-reading was substantial (κ=0.73 and κ=0.70, respectively). In 89/663 MRI-SIs (13.4%) local-reading and central-reading disagreed; 38/223 patients (17.0%) with pos-MRI (local-reading) were negative by central-reading; 51/440 patients (11.6%) with neg-MRI (local-reading) were positive by central-reading.In 163/582 patients eligible for applying ASAS criteria (28.0%), local-reading and central-reading disagreed on positive imaging (MRI-SI and/or X-SI; κ=0.68). In 46/582 patients (7.9%) a different evaluation resulted in a different classification; 18/582 patients (3.1%) classified no-SpA (central-reading) were axSpA by local-reading; 28/582 patients (4.8%) classified axSpA (central-reading) were no-SpA by local-reading. Among axSpA patients (central-reading), 16/419 patients (3.8%) fulfilling imaging-arm by central-reading fulfilled clinical-arm by local-reading; 29/419 patients (6.9%) fulfilling clinical-arm by central-reading fulfilled also imaging-arm by local-reading.ConclusionsIn patients with recent onset IBP, trained readers and local rheumatologists/radiologists agree well on recognising a pos-MRI. While disagreeing in 28% of the patients on positive imaging (MRI-SI and/or X-SI), classification of only 7.9% of the patients changed based on a different evaluation of images, showing the ASAS axSpA criteria's robustness.</abstract><cop>England</cop><pub>Elsevier Limited</pub><pmid>24962871</pmid><doi>10.1136/annrheumdis-2014-205432</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-8454-7067</orcidid><orcidid>https://orcid.org/0000-0002-5781-158X</orcidid></addata></record> |
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subjects | Adolescent Adult Agreements Back pain Back Pain - etiology Back Pain - pathology Classification Clinical medicine Clinical trials Cohort Studies Edema Female Humans Laboratories Life Sciences Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged Observer Variation Patients Prospective Studies Radiology - standards Reading Rheumatology - standards Sacroiliac Joint - pathology Sacroiliitis - complications Sacroiliitis - pathology Severity of Illness Index Spondylarthropathies - complications Spondylarthropathies - pathology Spondylitis, Ankylosing - complications Spondylitis, Ankylosing - pathology Young Adult |
title | Classification of axial SpA based on positive imaging (radiographs and/or MRI of the sacroiliac joints) by local rheumatologists or radiologists versus central trained readers in the DESIR cohort |
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