Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

Mice out of step on X inactivation X-chromosome inactivation is an essential process in female mammals that compensates for the presence of two X-chromosomes by suppressing gene expression from one of them. A study of the early developmental time course of X-chromosome inactivation in mice, rabbits...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2011-04, Vol.472 (7343), p.370-374
Hauptverfasser:	Okamoto, Ikuhiro, Patrat, Catherine, Thépot, Dominique, Peynot, Nathalie, Fauque, Patricia, Daniel, Nathalie, Diabangouaya, Patricia, Wolf, Jean-Philippe, Renard, Jean-Paul, Duranthon, Véronique, Heard, Edith
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/2086 631/208/182 631/337/176/1433 Animal development Animals Biological and medical sciences Biological Evolution Blastocyst - metabolism Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Chromosomes Chromosomes, Mammalian - genetics Compensation Development Biology Dosage Compensation, Genetic - genetics Embryo, Mammalian - embryology Embryo, Mammalian - metabolism Embryonic growth stage Eutherians Female Females Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental - genetics Genes, X-Linked - genetics Genetic aspects Genetic engineering Genomic Imprinting - genetics Histones - metabolism Humanities and Social Sciences Humans Hypoxanthine Phosphoribosyltransferase - genetics Inactivation letter Life Sciences Male Males Mammals Mammals - embryology Mammals - genetics Mice Molecular and cellular biology multidisciplinary Observations Parthenogenesis Physiological aspects Rabbits Reproductive Biology RNA, Long Noncoding RNA, Untranslated - genetics Science Science (multidisciplinary) Species Specificity Up-Regulation - genetics X Chromosome - genetics X chromosome inactivation X Chromosome Inactivation - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!