Enantioselective synthesis of bio-relevant 3,5-diaryl pyrazolines

The straightforward asymmetric construction of bio-relevant Δ(2)-pyrazolines having either N-(thio)amide or N-acetyl functional groups and flanked by aryl substituents such as phenol at C3 and C5 has been achieved through an enantioselective phase transfer organocatalytic addition of N-Boc hydrazine...

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Veröffentlicht in:	Organic & biomolecular chemistry 2012-05, Vol.10 (19), p.3946-3954
Hauptverfasser:	Mahé, Olivier, Dez, Isabelle, Levacher, Vincent, Brière, Jean-François
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - chemistry Chemical Sciences Molecular Structure Monoamine Oxidase Inhibitors - chemical synthesis Monoamine Oxidase Inhibitors - pharmacology Organic chemistry Pyrazoles - chemical synthesis Pyrazoles - pharmacology Stereoisomerism
Online-Zugang:	Volltext
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