Auto-antibodies to vascular endothelial cadherin in humans: association with autoimmune diseases

To identify patients with autoimmune diseases who are at high risk of developing vascular cell dysfunction, early biomarkers must be identified. This study was designed to detect and characterize circulating autoantibodies to VE-cadherin (AAVEs) in patients with early-stage autoimmune diseases. An e...

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Veröffentlicht in:	Laboratory investigation 2013-11, Vol.93 (11), p.1194-1202
Hauptverfasser:	Bouillet, L, Baudet, A E, Deroux, A, Sidibé, A, Dumestre-Perard, C, Mannic, T, Treillard, B, Arboleas, M A, Chiquet, C A, Gulino-Debrac, D G, Vilgrain, I Y
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/2152/2153/1291 631/80/79/1902 692/699/249/1313 Antigens, CD Antigens, CD - chemistry Antigens, CD - immunology Arthritis, Rheumatoid Arthritis, Rheumatoid - immunology Autoantibodies Autoantibodies - blood Autoantigens Autoantigens - chemistry Autoimmune Diseases Autoimmune Diseases - immunology Behcet Syndrome Behcet Syndrome - immunology Cadherins Cadherins - chemistry Cadherins - immunology Case-Control Studies Enzyme-Linked Immunosorbent Assay Epitopes Epitopes - chemistry Human Umbilical Vein Endothelial Cells Humans Immunoglobulin G Immunoglobulin G - blood Laboratory Medicine Life Sciences Lupus Erythematosus, Systemic Lupus Erythematosus, Systemic - immunology Medicine Medicine & Public Health Microbiology and Parasitology Pathology Peptide Fragments Peptide Fragments - chemistry Peptide Fragments - immunology research-article Scleroderma, Systemic Scleroderma, Systemic - immunology
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