Application of acute phase protein measurements in veterinary clinical chemistry
The body's early defence in response to trauma, inflammation or infection, the acute phase response, is a complex set of systemic reactions seen shortly after exposure to a triggering event. One of the many components is an acute phase protein response in which increased hepatic synthesis leads...
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| Veröffentlicht in: | Veterinary research (Paris) 2004-03, Vol.35 (2), p.163-187 |
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| container_title | Veterinary research (Paris) |
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| creator | PETERSEN, Henrik Hagbard NIELSEN, Jens Peter HEEGAARD, Peter Mikael |
| description | The body's early defence in response to trauma, inflammation or infection, the acute phase response, is a complex set of systemic reactions seen shortly after exposure to a triggering event. One of the many components is an acute phase protein response in which increased hepatic synthesis leads to increased serum concentration of positive acute phase proteins. The serum concentration of these acute phase proteins returns to base levels when the triggering factor is no longer present. This paper provides a review of the acute phase proteins haptoglobin, C-reactive protein and serum amyloid A and their possible use as non-specific indicators of health in large animal veterinary medicine such as in the health status surveillance of pigs at the herd level, for the detection of mastitis in dairy cattle and for the prognosis of respiratory diseases in horses. |
| doi_str_mv | 10.1051/vetres:2004002 |
| format | Article |
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One of the many components is an acute phase protein response in which increased hepatic synthesis leads to increased serum concentration of positive acute phase proteins. The serum concentration of these acute phase proteins returns to base levels when the triggering factor is no longer present. This paper provides a review of the acute phase proteins haptoglobin, C-reactive protein and serum amyloid A and their possible use as non-specific indicators of health in large animal veterinary medicine such as in the health status surveillance of pigs at the herd level, for the detection of mastitis in dairy cattle and for the prognosis of respiratory diseases in horses.</description><identifier>ISSN: 0928-4249</identifier><identifier>EISSN: 1297-9716</identifier><identifier>DOI: 10.1051/vetres:2004002</identifier><identifier>PMID: 15099494</identifier><language>eng</language><publisher>Les Ulis: EDP Sciences</publisher><subject>Acute-Phase Proteins - metabolism ; Animal biology ; Animal genetics ; Animals ; Apolipoproteins - blood ; Biochemistry, Molecular Biology ; Biological and medical sciences ; C-Reactive Protein - metabolism ; Cattle ; Cell Behavior ; Cellular Biology ; Female ; Fundamental and applied biological sciences. 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One of the many components is an acute phase protein response in which increased hepatic synthesis leads to increased serum concentration of positive acute phase proteins. The serum concentration of these acute phase proteins returns to base levels when the triggering factor is no longer present. This paper provides a review of the acute phase proteins haptoglobin, C-reactive protein and serum amyloid A and their possible use as non-specific indicators of health in large animal veterinary medicine such as in the health status surveillance of pigs at the herd level, for the detection of mastitis in dairy cattle and for the prognosis of respiratory diseases in horses.</description><subject>Acute-Phase Proteins - metabolism</subject><subject>Animal biology</subject><subject>Animal genetics</subject><subject>Animals</subject><subject>Apolipoproteins - blood</subject><subject>Biochemistry, Molecular Biology</subject><subject>Biological and medical sciences</subject><subject>C-Reactive Protein - metabolism</subject><subject>Cattle</subject><subject>Cell Behavior</subject><subject>Cellular Biology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetics</subject><subject>Haptoglobins - metabolism</subject><subject>Horse Diseases - blood</subject><subject>Horses</subject><subject>Immunology</subject><subject>Life Sciences</subject><subject>Mastitis, Bovine - blood</subject><subject>Microbiology</subject><subject>Microbiology and Parasitology</subject><subject>Molecular biology</subject><subject>Neurons and Cognition</subject><subject>Respiratory Tract Infections - blood</subject><subject>Respiratory Tract Infections - veterinary</subject><subject>Santé publique et épidémiologie</subject><subject>Serum Amyloid A Protein</subject><subject>Swine</subject><subject>Swine Diseases - blood</subject><issn>0928-4249</issn><issn>1297-9716</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkMtr3DAQh0VJSTaPa4_BlwRy8Hb0tNXbEtpuYaE9NGehlUesgh9byQ7sfx8tNm0vGiS--WnmI-QThTUFST-_4RgxfWEAAoB9ICvKdFXqiqoLsgLN6lIwoa_IdUqvAFRxKS7JFZWgtdBiRX5tjsc2ODuGoS8GX1g3jVgcDzblMw4jhr7o0KYpYof9mIp8z39iDL2Np8K1oc_dbeEO2IU0xtMt-ehtm_BuqTfk5dvX38_bcvfz-4_nza50XMuxpIxxr3ylOOgKvJdCAkPQNSjPtbfe6sbx2jvVKCflXqGrGi3Ru0bUwu75DXmacw-2NccYujyOGWww283OnN8ANLCa8Tea2ceZzRv9mTCNJs_qsG1tj8OUTEVryVh1Btcz6OKQUkT_N5mCOfs2s2-z-M4N90vytO-w-YcvgjPwsAA2ZU8-2t6F9B-nGFca-Ds3q4pF</recordid><startdate>20040301</startdate><enddate>20040301</enddate><creator>PETERSEN, Henrik Hagbard</creator><creator>NIELSEN, Jens Peter</creator><creator>HEEGAARD, Peter Mikael</creator><general>EDP Sciences</general><general>BioMed Central</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><orcidid>https://orcid.org/0000-0002-9955-6003</orcidid></search><sort><creationdate>20040301</creationdate><title>Application of acute phase protein measurements in veterinary clinical chemistry</title><author>PETERSEN, Henrik Hagbard ; NIELSEN, Jens Peter ; HEEGAARD, Peter Mikael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-1223f6f7630970ff54502e09806f39fafa9dc38fc6d6c55b6ec7d95efcd484ab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Acute-Phase Proteins - metabolism</topic><topic>Animal biology</topic><topic>Animal genetics</topic><topic>Animals</topic><topic>Apolipoproteins - blood</topic><topic>Biochemistry, Molecular Biology</topic><topic>Biological and medical sciences</topic><topic>C-Reactive Protein - metabolism</topic><topic>Cattle</topic><topic>Cell Behavior</topic><topic>Cellular Biology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. 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| ispartof | Veterinary research (Paris), 2004-03, Vol.35 (2), p.163-187 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Acute-Phase Proteins - metabolism Animal biology Animal genetics Animals Apolipoproteins - blood Biochemistry, Molecular Biology Biological and medical sciences C-Reactive Protein - metabolism Cattle Cell Behavior Cellular Biology Female Fundamental and applied biological sciences. Psychology Genetics Haptoglobins - metabolism Horse Diseases - blood Horses Immunology Life Sciences Mastitis, Bovine - blood Microbiology Microbiology and Parasitology Molecular biology Neurons and Cognition Respiratory Tract Infections - blood Respiratory Tract Infections - veterinary Santé publique et épidémiologie Serum Amyloid A Protein Swine Swine Diseases - blood |
| title | Application of acute phase protein measurements in veterinary clinical chemistry |
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