Trans isomers of long-chain n-3 polyunsaturated fatty acids in tissue lipid classes of rats fed with heated linseed oil
The isomerization of linolenic acid into mono- and di-trans isomers takes place during heat treatment. One of these compounds, 18:3 delta 9c, 12c, 15t can be desaturated and elongated to form, in particular, the trans isomers of eicosapentaenoic and docosahexaenoic acids. This study was undertaken t...
Gespeichert in:
| Veröffentlicht in: | Reproduction, nutrition, development nutrition, development, 1998, Vol.38 (1), p.17-29 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 29 |
|---|---|
| container_issue | 1 |
| container_start_page | 17 |
| container_title | Reproduction, nutrition, development |
| container_volume | 38 |
| creator | GRANDGIRARD, A PICONNEAUX, A SEBEDIO, J.-L JULLIARD, F |
| description | The isomerization of linolenic acid into mono- and di-trans isomers takes place during heat treatment. One of these compounds, 18:3 delta 9c, 12c, 15t can be desaturated and elongated to form, in particular, the trans isomers of eicosapentaenoic and docosahexaenoic acids. This study was undertaken to observe the incorporation of these trans long-chain n-3 polyunsaturated fatty acids into the lipid classes of several tissues. Rats were fed for 8 weeks with heated linseed oil containing high levels of trans linolenic acid isomers. The lipid classes of the liver, kidney, heart and adrenals of these rats contained various levels of these compounds. The 20:5 delta 5c, 8c, 11c, 14c, 17t represented between 80 and 90% of the total 20:5 in the phospholipids, but 22:5 delta 7c, 10c, 13c, 16c, 19t and mainly 22:6 delta 4c, 7c, 10c, 13c, 16c, 19t were only present in small quantities. This may indicate that the cis fatty acids are better metabolized in these cases. Among the tissues studied, it was interesting to note a high level of 22:5 delta 19t in the adrenals, particularly in cholesterol esters. |
| doi_str_mv | 10.1051/rnd:19980102 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_00900138v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79902586</sourcerecordid><originalsourceid>FETCH-LOGICAL-c387t-9e6058e333f6f66922a6601d0caae5d40750f1c2624e82d1bc524be65bccd48b3</originalsourceid><addsrcrecordid>eNpFkc9rFDEUgIModfvj5lXIQQTBqS_JJJn0VopaYaGXeg6ZTMaNZCdr3kzL_vem3bWeHrz3ve_yEfKOwSUDyb6UabhixnTAgL8iK8aNboyG7jVZgeGqkbzTb8kp4m8AkFKrE3JiFCjdqhV5vC9uQhoxb0NBmkea8vSr8RsXJzo1gu5y2i8Tunkpbg4DHd0876nzcahfE50j4hJoirs4UJ8cYni2VBjpWPnHOG_oJjz_pjhhqDPHdE7ejC5huDjOM_Lz29f7m9tmfff9x831uvGi03NjggLZBSHEqEalDOdOKWADeOeCHFrQEkbmueJt6PjAei952wcle--HtuvFGfl08G5csrsSt67sbXbR3l6v7dMOwAAw0T2wyn48sLuS_ywBZ7uN6ENKbgp5QauNAS47VcHPB9CXjFjC-GJmYJ-a2NrE_mtS8fdH79Jvw_ACHyPU-4fj3aF3aaxFfMT_TqWZMFz8Bbf-lEY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79902586</pqid></control><display><type>article</type><title>Trans isomers of long-chain n-3 polyunsaturated fatty acids in tissue lipid classes of rats fed with heated linseed oil</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>EDP Sciences</source><source>Alma/SFX Local Collection</source><creator>GRANDGIRARD, A ; PICONNEAUX, A ; SEBEDIO, J.-L ; JULLIARD, F</creator><creatorcontrib>GRANDGIRARD, A ; PICONNEAUX, A ; SEBEDIO, J.-L ; JULLIARD, F</creatorcontrib><description>The isomerization of linolenic acid into mono- and di-trans isomers takes place during heat treatment. One of these compounds, 18:3 delta 9c, 12c, 15t can be desaturated and elongated to form, in particular, the trans isomers of eicosapentaenoic and docosahexaenoic acids. This study was undertaken to observe the incorporation of these trans long-chain n-3 polyunsaturated fatty acids into the lipid classes of several tissues. Rats were fed for 8 weeks with heated linseed oil containing high levels of trans linolenic acid isomers. The lipid classes of the liver, kidney, heart and adrenals of these rats contained various levels of these compounds. The 20:5 delta 5c, 8c, 11c, 14c, 17t represented between 80 and 90% of the total 20:5 in the phospholipids, but 22:5 delta 7c, 10c, 13c, 16c, 19t and mainly 22:6 delta 4c, 7c, 10c, 13c, 16c, 19t were only present in small quantities. This may indicate that the cis fatty acids are better metabolized in these cases. Among the tissues studied, it was interesting to note a high level of 22:5 delta 19t in the adrenals, particularly in cholesterol esters.</description><identifier>ISSN: 0926-5287</identifier><identifier>EISSN: 1297-9708</identifier><identifier>DOI: 10.1051/rnd:19980102</identifier><identifier>PMID: 9606746</identifier><identifier>CODEN: RNDED4</identifier><language>eng</language><publisher>Les Ulis: EDP Sciences</publisher><subject>Adrenal Glands - chemistry ; Animals ; Biological and medical sciences ; Development Biology ; Dietary Fats, Unsaturated - administration & dosage ; Fatty Acids, Omega-3 - analysis ; Feeding. Feeding behavior ; Food and Nutrition ; Fundamental and applied biological sciences. Psychology ; Hot Temperature ; Kidney - chemistry ; Life Sciences ; Linseed Oil - administration & dosage ; Lipids - analysis ; Liver - chemistry ; Myocardium - chemistry ; Phospholipids - analysis ; Rats ; Rats, Wistar ; Reproductive Biology ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>Reproduction, nutrition, development, 1998, Vol.38 (1), p.17-29</ispartof><rights>1999 INIST-CNRS</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-9e6058e333f6f66922a6601d0caae5d40750f1c2624e82d1bc524be65bccd48b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,3727,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1671392$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9606746$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00900138$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>GRANDGIRARD, A</creatorcontrib><creatorcontrib>PICONNEAUX, A</creatorcontrib><creatorcontrib>SEBEDIO, J.-L</creatorcontrib><creatorcontrib>JULLIARD, F</creatorcontrib><title>Trans isomers of long-chain n-3 polyunsaturated fatty acids in tissue lipid classes of rats fed with heated linseed oil</title><title>Reproduction, nutrition, development</title><addtitle>Reprod Nutr Dev</addtitle><description>The isomerization of linolenic acid into mono- and di-trans isomers takes place during heat treatment. One of these compounds, 18:3 delta 9c, 12c, 15t can be desaturated and elongated to form, in particular, the trans isomers of eicosapentaenoic and docosahexaenoic acids. This study was undertaken to observe the incorporation of these trans long-chain n-3 polyunsaturated fatty acids into the lipid classes of several tissues. Rats were fed for 8 weeks with heated linseed oil containing high levels of trans linolenic acid isomers. The lipid classes of the liver, kidney, heart and adrenals of these rats contained various levels of these compounds. The 20:5 delta 5c, 8c, 11c, 14c, 17t represented between 80 and 90% of the total 20:5 in the phospholipids, but 22:5 delta 7c, 10c, 13c, 16c, 19t and mainly 22:6 delta 4c, 7c, 10c, 13c, 16c, 19t were only present in small quantities. This may indicate that the cis fatty acids are better metabolized in these cases. Among the tissues studied, it was interesting to note a high level of 22:5 delta 19t in the adrenals, particularly in cholesterol esters.</description><subject>Adrenal Glands - chemistry</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Development Biology</subject><subject>Dietary Fats, Unsaturated - administration & dosage</subject><subject>Fatty Acids, Omega-3 - analysis</subject><subject>Feeding. Feeding behavior</subject><subject>Food and Nutrition</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hot Temperature</subject><subject>Kidney - chemistry</subject><subject>Life Sciences</subject><subject>Linseed Oil - administration & dosage</subject><subject>Lipids - analysis</subject><subject>Liver - chemistry</subject><subject>Myocardium - chemistry</subject><subject>Phospholipids - analysis</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Reproductive Biology</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0926-5287</issn><issn>1297-9708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkc9rFDEUgIModfvj5lXIQQTBqS_JJJn0VopaYaGXeg6ZTMaNZCdr3kzL_vem3bWeHrz3ve_yEfKOwSUDyb6UabhixnTAgL8iK8aNboyG7jVZgeGqkbzTb8kp4m8AkFKrE3JiFCjdqhV5vC9uQhoxb0NBmkea8vSr8RsXJzo1gu5y2i8Tunkpbg4DHd0876nzcahfE50j4hJoirs4UJ8cYni2VBjpWPnHOG_oJjz_pjhhqDPHdE7ejC5huDjOM_Lz29f7m9tmfff9x831uvGi03NjggLZBSHEqEalDOdOKWADeOeCHFrQEkbmueJt6PjAei952wcle--HtuvFGfl08G5csrsSt67sbXbR3l6v7dMOwAAw0T2wyn48sLuS_ywBZ7uN6ENKbgp5QauNAS47VcHPB9CXjFjC-GJmYJ-a2NrE_mtS8fdH79Jvw_ACHyPU-4fj3aF3aaxFfMT_TqWZMFz8Bbf-lEY</recordid><startdate>1998</startdate><enddate>1998</enddate><creator>GRANDGIRARD, A</creator><creator>PICONNEAUX, A</creator><creator>SEBEDIO, J.-L</creator><creator>JULLIARD, F</creator><general>EDP Sciences</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope></search><sort><creationdate>1998</creationdate><title>Trans isomers of long-chain n-3 polyunsaturated fatty acids in tissue lipid classes of rats fed with heated linseed oil</title><author>GRANDGIRARD, A ; PICONNEAUX, A ; SEBEDIO, J.-L ; JULLIARD, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-9e6058e333f6f66922a6601d0caae5d40750f1c2624e82d1bc524be65bccd48b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adrenal Glands - chemistry</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Development Biology</topic><topic>Dietary Fats, Unsaturated - administration & dosage</topic><topic>Fatty Acids, Omega-3 - analysis</topic><topic>Feeding. Feeding behavior</topic><topic>Food and Nutrition</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hot Temperature</topic><topic>Kidney - chemistry</topic><topic>Life Sciences</topic><topic>Linseed Oil - administration & dosage</topic><topic>Lipids - analysis</topic><topic>Liver - chemistry</topic><topic>Myocardium - chemistry</topic><topic>Phospholipids - analysis</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Reproductive Biology</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>GRANDGIRARD, A</creatorcontrib><creatorcontrib>PICONNEAUX, A</creatorcontrib><creatorcontrib>SEBEDIO, J.-L</creatorcontrib><creatorcontrib>JULLIARD, F</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><jtitle>Reproduction, nutrition, development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>GRANDGIRARD, A</au><au>PICONNEAUX, A</au><au>SEBEDIO, J.-L</au><au>JULLIARD, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Trans isomers of long-chain n-3 polyunsaturated fatty acids in tissue lipid classes of rats fed with heated linseed oil</atitle><jtitle>Reproduction, nutrition, development</jtitle><addtitle>Reprod Nutr Dev</addtitle><date>1998</date><risdate>1998</risdate><volume>38</volume><issue>1</issue><spage>17</spage><epage>29</epage><pages>17-29</pages><issn>0926-5287</issn><eissn>1297-9708</eissn><coden>RNDED4</coden><abstract>The isomerization of linolenic acid into mono- and di-trans isomers takes place during heat treatment. One of these compounds, 18:3 delta 9c, 12c, 15t can be desaturated and elongated to form, in particular, the trans isomers of eicosapentaenoic and docosahexaenoic acids. This study was undertaken to observe the incorporation of these trans long-chain n-3 polyunsaturated fatty acids into the lipid classes of several tissues. Rats were fed for 8 weeks with heated linseed oil containing high levels of trans linolenic acid isomers. The lipid classes of the liver, kidney, heart and adrenals of these rats contained various levels of these compounds. The 20:5 delta 5c, 8c, 11c, 14c, 17t represented between 80 and 90% of the total 20:5 in the phospholipids, but 22:5 delta 7c, 10c, 13c, 16c, 19t and mainly 22:6 delta 4c, 7c, 10c, 13c, 16c, 19t were only present in small quantities. This may indicate that the cis fatty acids are better metabolized in these cases. Among the tissues studied, it was interesting to note a high level of 22:5 delta 19t in the adrenals, particularly in cholesterol esters.</abstract><cop>Les Ulis</cop><pub>EDP Sciences</pub><pmid>9606746</pmid><doi>10.1051/rnd:19980102</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0926-5287 |
| ispartof | Reproduction, nutrition, development, 1998, Vol.38 (1), p.17-29 |
| issn | 0926-5287 1297-9708 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_00900138v1 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; EDP Sciences; Alma/SFX Local Collection |
| subjects | Adrenal Glands - chemistry Animals Biological and medical sciences Development Biology Dietary Fats, Unsaturated - administration & dosage Fatty Acids, Omega-3 - analysis Feeding. Feeding behavior Food and Nutrition Fundamental and applied biological sciences. Psychology Hot Temperature Kidney - chemistry Life Sciences Linseed Oil - administration & dosage Lipids - analysis Liver - chemistry Myocardium - chemistry Phospholipids - analysis Rats Rats, Wistar Reproductive Biology Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | Trans isomers of long-chain n-3 polyunsaturated fatty acids in tissue lipid classes of rats fed with heated linseed oil |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T17%3A40%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Trans%20isomers%20of%20long-chain%20n-3%20polyunsaturated%20fatty%20acids%20in%20tissue%20lipid%20classes%20of%20rats%20fed%20with%20heated%20linseed%20oil&rft.jtitle=Reproduction,%20nutrition,%20development&rft.au=GRANDGIRARD,%20A&rft.date=1998&rft.volume=38&rft.issue=1&rft.spage=17&rft.epage=29&rft.pages=17-29&rft.issn=0926-5287&rft.eissn=1297-9708&rft.coden=RNDED4&rft_id=info:doi/10.1051/rnd:19980102&rft_dat=%3Cproquest_hal_p%3E79902586%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79902586&rft_id=info:pmid/9606746&rfr_iscdi=true |