Fish as a model in investigations about the relationship between oxygen consumption and hydroxyl radical production in permeabilized muscle fibers

Mitochondrion is the main production site for reactive oxygen species (ROS). In endotherms, the existence of a positive relationship between ROS production and metabolic rate is acknowledged. But, little is known about ectotherms, especially fish, with a metabolic rate dependent on the environmental...

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Veröffentlicht in:Mitochondrion 2010-08, Vol.10 (5), p.555-558
Hauptverfasser: Mortelette, H, Moisan, C, Sébert, P, Belhomme, M, Amérand, A
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container_end_page 558
container_issue 5
container_start_page 555
container_title Mitochondrion
container_volume 10
creator Mortelette, H
Moisan, C
Sébert, P
Belhomme, M
Amérand, A
description Mitochondrion is the main production site for reactive oxygen species (ROS). In endotherms, the existence of a positive relationship between ROS production and metabolic rate is acknowledged. But, little is known about ectotherms, especially fish, with a metabolic rate dependent on the environmental temperature. The maximal oxygen consumption and the production of highly reactive hydroxyl radicals by permeabilized red muscles of yellow and silver eels and trouts were measured concomitantly and compared to those of rats chosen for their comparable body mass, but different metabolic rate. The positive correlation found in fish between the metabolic rate and the ROS production showed a shift with respect to mammals.
doi_str_mv 10.1016/j.mito.2010.05.002
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1872-8278
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Animals
Eels
Eels - metabolism
Female
Human health and pathology
Hydroxyl Radical
Hydroxyl Radical - metabolism
Life Sciences
Male
Muscles
Muscles - metabolism
Oxygen Consumption
Rats
Rats, Sprague-Dawley
Tissues and Organs
Trout
Trout - metabolism
title Fish as a model in investigations about the relationship between oxygen consumption and hydroxyl radical production in permeabilized muscle fibers
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