Could modifications of signalling pathways activated after ICSI induce a potential risk of epigenetic defects?

A calcium signal during oocyte or egg activation is a conserved event in virtually all species analyzed so far. This signal, that is in the form of calcium oscillations in mammals, is spatially and temporally controlled and is mainly supported by calcium release from internal calcium stores, but how...

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Veröffentlicht in:	The International journal of developmental biology 2011, Vol.55 (2), p.143-152
Hauptverfasser:	Ciapa, Brigitte, Arnoult, Christophe
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Epigenesis, Genetic Humans Life Sciences Neurons and Cognition Risk Factors Signal Transduction Sperm Injections, Intracytoplasmic - methods Sperm-Ovum Interactions
Online-Zugang:	Volltext
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