Influence of Calcium-Induced Aggregation on the Sensitivity of Aminobis(methylenephosphonate)-Containing Potential MRI Contrast Agents

A novel class of 1,4,7,10-tetraazacyclododecane-1,4,7-tris(methylenecarboxylic) acid (DO3A)-based lanthanide complexes with relaxometric response to Ca2+ was synthesized, and their physicochemical properties were investigated. Four macrocyclic ligands containing an alkyl-aminobis(methylenephosphonat...

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Veröffentlicht in:	Inorganic chemistry 2011-07, Vol.50 (14), p.6472-6481
Hauptverfasser:	Henig, Jörg, Mamedov, Ilgar, Fouskova, Petra, Tóth, Éva, Logothetis, Nikos K, Angelovski, Goran, Mayer, Hermann A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry, Molecular Biology Calcium Calcium - chemistry Chelating Agents Chelating Agents - chemical synthesis Chelating Agents - chemistry Contrast Media Contrast Media - chemical synthesis Contrast Media - chemistry Lanthanoid Series Elements Lanthanoid Series Elements - chemistry Life Sciences Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Molecular Structure Organometallic Compounds Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Stereoisomerism
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