Evolution of GPCR: Change and continuity

Once introduced into the very early eukaryotic blueprint, seven-transmembrane receptors soon became the central and versatile components of the evolutionary highly successful G protein-coupled transmembrane signaling mechanism. In contrast to all other components of this signal transduction pathway,...

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Veröffentlicht in:	Molecular and cellular endocrinology 2011-01, Vol.331 (2), p.170-178
Hauptverfasser:	Strotmann, Rainer, Schröck, Kristin, Böselt, Iris, Stäubert, Claudia, Russ, Andreas, Schöneberg, Torsten
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Conserved Sequence Evolution Evolution, Molecular functional diversity G-protein coupled receptors genes Genome GPCR Humans Phylogeny Population genetics Protein Conformation Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism sequence analysis Sequence Analysis, Protein Seven-transmembrane receptor Signal Transduction vertebrates
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