Synthesis and Evaluation of Bis-Thiazolium Salts as Potential Antimalarial Drug

An innovative therapeutic approach based on the use of dicationic derivatives was previously designed to inhibit the biosynthesis of phosphatidylcholine in Plasmodium spp. Among these, bis-thiazolium salts were shown to block proliferation of the malaria parasite at concentrations in the low nanomol...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ChemMedChem 2010, Vol.5, p.1102-1109
Hauptverfasser:	Caldarelli, Sergio A., Duckert, Jean-Frédéric, Wein, Sharon, Calas, Michèle, Perigaud, Christian, Vial, Henri, Peyrottes, Suzanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Sciences Organic chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!