P75 neurotrophin receptor is sequestered in the Golgi apparatus of the U-87 MG human glioblastoma cell line

The P75 neurotrophin receptor (p75NTR) is a cell surface receptor that can induce apoptosis in many cell types. This receptor plays a major role in the development of the central nervous system and is expressed in some adult brain cells. Its implication in cell apoptosis or survival is probably of m...

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Veröffentlicht in:	International journal of oncology 2011-02, Vol.38 (2), p.391-399
Hauptverfasser:	GIRAUD, Stéphanie, LOUM, Elodie, BESSETTE, Barbara, MATHONNET, Muriel, LALLOUE, Fabrice
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological and medical sciences Blotting, Western Brain Neoplasms Brain Neoplasms - metabolism Brain Neoplasms - pathology Cancer Cellular Biology Enzyme-Linked Immunosorbent Assay Flow Cytometry Fluorescent Antibody Technique Glioblastoma Glioblastoma - metabolism Glioblastoma - pathology Glycoside Hydrolases Glycoside Hydrolases - metabolism Golgi Apparatus Golgi Apparatus - metabolism Humans Immunoenzyme Techniques Life Sciences Medical sciences Membrane Microdomains Membrane Microdomains - metabolism Neurobiology Neurology Neurons and Cognition Receptor, Nerve Growth Factor Receptor, Nerve Growth Factor - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger RNA, Messenger - genetics Subcellular Fractions Tumor Cells, Cultured Tumors Tumors of the nervous system. Phacomatoses
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