Efficacy and toxicity of mitomycin, ifosfamide, and cisplatin (MIP) in patients with inoperable non-small cell lung cancer

Seventy-two patients with advanced stage IIIB (42%) or stage IV (58%) non-small cell lung cancer (median age 57 years, Karnofsky PS 60–100) were treated with mitomycin C (6 mg/m 2, day 1), ifosfamide (1500 mg/m 2, days 1–3), and cisplatin (30 mg/m 2, days 1–3) every 4 weeks. The objective response r...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 1996-02, Vol.14 (1), p.109-117
Hauptverfasser:	Urban, Thierry, Bedin, Arnaud, Baud, Mariette, Chouaid, Christos, Febvre, Michel, Lebeau, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Advanced non-small cell lung cancer Aged Antibiotics, Antineoplastic Antibiotics, Antineoplastic - administration & dosage Antibiotics, Antineoplastic - adverse effects Antineoplastic agents Antineoplastic Agents, Alkylating Antineoplastic Agents, Alkylating - administration & dosage Antineoplastic Agents, Alkylating - adverse effects Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Carcinoma, Non-Small-Cell Lung Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - therapy Chemotherapy Cisplatin Cisplatin - administration & dosage Cisplatin - adverse effects Combined Modality Therapy Dose-Response Relationship, Drug Efficacy Female Humans Ifosfamide Ifosfamide - administration & dosage Ifosfamide - adverse effects Infusions, Intravenous Life Sciences Lung Neoplasms Lung Neoplasms - diagnosis Lung Neoplasms - mortality Lung Neoplasms - therapy Male Medical sciences Middle Aged Mitomycins Mitomycins - administration & dosage Mitomycins - adverse effects Neoplasm Staging Pharmacology. Drug treatments Prospective Studies Radiotherapy, Adjuvant Santé publique et épidémiologie Survival Rate Toxicity Treatment Outcome
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