The vasoactive intestinal peptide-receptor system is involved in human glioblastoma cell migration

Abstract Glioblastoma multiforme (GBM) is the most aggressive form of brain tumor in adults. This cancer has an infiltrative nature and the median survival of patients is about one year. Vasoactive intestinal peptide (VIP) belongs to a structurally related family of polypeptides and is a major regul...

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Veröffentlicht in:	Neuropeptides (Edinburgh) 2010-10, Vol.44 (5), p.373-383
Hauptverfasser:	Cochaud, Stéphanie, Chevrier, Lucie, Meunier, Annie-Claire, Brillet, Thomas, Chadéneau, Corinne, Muller, Jean-Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin cytoskeleton Advanced Basic Science Antagonists Biological and medical sciences Blotting, Western Cancer Cell Line, Tumor Cell Movement Cell Movement - drug effects Cell Movement - physiology Cell Proliferation Cell Proliferation - drug effects Cells, Cultured Cellular Biology Cyclic AMP Cyclic AMP - metabolism Endocrinology & Metabolism Fundamental and applied biological sciences. Psychology Glioblastoma cell lines Humans Immunohistochemistry Life Sciences Medical sciences Migration Neurology Pharmaceutical sciences Pharmacology Polymerase Chain Reaction Proliferation Receptors, Vasoactive Intestinal Peptide Receptors, Vasoactive Intestinal Peptide - agonists Receptors, Vasoactive Intestinal Peptide - antagonists & inhibitors Receptors, Vasoactive Intestinal Peptide - metabolism Small GTPases Tumors of the nervous system. Phacomatoses Vasoactive Intestinal Peptide Vasoactive Intestinal Peptide - analogs & derivatives Vasoactive Intestinal Peptide - pharmacology Vertebrates: endocrinology VIP receptors
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