Semipermeable membrane devices link site-specific contaminants to effects: PART II – A comparison of lingering Exxon Valdez oil with other potential sources of CYP1A inducers in Prince William Sound, Alaska
We deployed semipermeable membrane devices (SPMDs) on beaches for 28 days at 53 sites in Prince William Sound (PWS), Alaska, to evaluate the induction potential from suspected sources of cytochrome P450 1A (CYP1A)-inducing contaminants. Sites were selected to assess known point sources, or were chos...
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| Veröffentlicht in: | Marine environmental research 2008-12, Vol.66 (5), p.487-498 |
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| creator | Short, Jeffrey W. Springman, Kathrine R. Lindeberg, Mandy R. Holland, Larry G. Larsen, Marie L. Sloan, Catherine A. Khan, Colin Hodson, Peter V. Rice, Stanley D. |
| description | We deployed semipermeable membrane devices (SPMDs) on beaches for 28 days at 53 sites in Prince William Sound (PWS), Alaska, to evaluate the induction potential from suspected sources of cytochrome P450 1A (CYP1A)-inducing contaminants. Sites were selected to assess known point sources, or were chosen randomly to evaluate the region-wide sources. After deployment, SPMD extracts were analyzed chemically for persistent organic pollutants (POPs) and polycyclic aromatic hydrocarbons (PAH). These results were compared with hepatic CYP1A enzyme activity of juvenile rainbow trout injected with the same extracts prior to clean-up for the chemical analyses. Increased CYP1A activity was strongly associated with PAH concentrations in extracts, especially chrysene homologues but was not associated with POPs. The only apparent sources of chrysene homologues were lingering oil from Exxon Valdez, asphalt and bunker fuels released from storage tanks during the 1964 Alaska earthquake, creosote leaching from numerous pilings at one site, and PAH-contaminated sediments at Cordova Harbor. Our results indicate that PWS is remarkably free of pollution from PAH when nearby sources are absent as well as from pesticides and PCBs generally. |
| doi_str_mv | 10.1016/j.marenvres.2008.08.007 |
| format | Article |
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Sites were selected to assess known point sources, or were chosen randomly to evaluate the region-wide sources. After deployment, SPMD extracts were analyzed chemically for persistent organic pollutants (POPs) and polycyclic aromatic hydrocarbons (PAH). These results were compared with hepatic CYP1A enzyme activity of juvenile rainbow trout injected with the same extracts prior to clean-up for the chemical analyses. Increased CYP1A activity was strongly associated with PAH concentrations in extracts, especially chrysene homologues but was not associated with POPs. The only apparent sources of chrysene homologues were lingering oil from Exxon Valdez, asphalt and bunker fuels released from storage tanks during the 1964 Alaska earthquake, creosote leaching from numerous pilings at one site, and PAH-contaminated sediments at Cordova Harbor. Our results indicate that PWS is remarkably free of pollution from PAH when nearby sources are absent as well as from pesticides and PCBs generally.</description><identifier>ISSN: 0141-1136</identifier><identifier>EISSN: 1879-0291</identifier><identifier>DOI: 10.1016/j.marenvres.2008.08.007</identifier><identifier>PMID: 18845332</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Alaska ; Animal and plant ecology ; Animal, plant and microbial ecology ; Animals ; Applied ecology ; Biological and medical sciences ; Biological Availability ; Cytochrome P-450 CYP1A1 - metabolism ; Ecotoxicology, biological effects of pollution ; Environmental Monitoring - instrumentation ; Environmental Monitoring - methods ; Enzyme Induction - drug effects ; Fundamental and applied biological sciences. Psychology ; Marine ; Oil spills ; Oncorhynchus mykiss ; Oncorhynchus mykiss - metabolism ; PAH ; PCB ; Petroleum ; Pollution monitoring ; Sea water ecosystems ; Sources ; SPMD ; Synecology ; Water Pollutants, Chemical - toxicity</subject><ispartof>Marine environmental research, 2008-12, Vol.66 (5), p.487-498</ispartof><rights>2008</rights><rights>2009 INIST-CNRS</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c513t-b02ee363527458a83baeda402ea38848ed0581541f10c1f3294c3265ad2be9df3</citedby><cites>FETCH-LOGICAL-c513t-b02ee363527458a83baeda402ea38848ed0581541f10c1f3294c3265ad2be9df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S014111360800202X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20887598$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18845332$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00563050$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Short, Jeffrey W.</creatorcontrib><creatorcontrib>Springman, Kathrine R.</creatorcontrib><creatorcontrib>Lindeberg, Mandy R.</creatorcontrib><creatorcontrib>Holland, Larry G.</creatorcontrib><creatorcontrib>Larsen, Marie L.</creatorcontrib><creatorcontrib>Sloan, Catherine A.</creatorcontrib><creatorcontrib>Khan, Colin</creatorcontrib><creatorcontrib>Hodson, Peter V.</creatorcontrib><creatorcontrib>Rice, Stanley D.</creatorcontrib><title>Semipermeable membrane devices link site-specific contaminants to effects: PART II – A comparison of lingering Exxon Valdez oil with other potential sources of CYP1A inducers in Prince William Sound, Alaska</title><title>Marine environmental research</title><addtitle>Mar Environ Res</addtitle><description>We deployed semipermeable membrane devices (SPMDs) on beaches for 28 days at 53 sites in Prince William Sound (PWS), Alaska, to evaluate the induction potential from suspected sources of cytochrome P450 1A (CYP1A)-inducing contaminants. Sites were selected to assess known point sources, or were chosen randomly to evaluate the region-wide sources. After deployment, SPMD extracts were analyzed chemically for persistent organic pollutants (POPs) and polycyclic aromatic hydrocarbons (PAH). These results were compared with hepatic CYP1A enzyme activity of juvenile rainbow trout injected with the same extracts prior to clean-up for the chemical analyses. Increased CYP1A activity was strongly associated with PAH concentrations in extracts, especially chrysene homologues but was not associated with POPs. The only apparent sources of chrysene homologues were lingering oil from Exxon Valdez, asphalt and bunker fuels released from storage tanks during the 1964 Alaska earthquake, creosote leaching from numerous pilings at one site, and PAH-contaminated sediments at Cordova Harbor. 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Psychology</topic><topic>Marine</topic><topic>Oil spills</topic><topic>Oncorhynchus mykiss</topic><topic>Oncorhynchus mykiss - metabolism</topic><topic>PAH</topic><topic>PCB</topic><topic>Petroleum</topic><topic>Pollution monitoring</topic><topic>Sea water ecosystems</topic><topic>Sources</topic><topic>SPMD</topic><topic>Synecology</topic><topic>Water Pollutants, Chemical - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Short, Jeffrey W.</creatorcontrib><creatorcontrib>Springman, Kathrine R.</creatorcontrib><creatorcontrib>Lindeberg, Mandy R.</creatorcontrib><creatorcontrib>Holland, Larry G.</creatorcontrib><creatorcontrib>Larsen, Marie L.</creatorcontrib><creatorcontrib>Sloan, Catherine A.</creatorcontrib><creatorcontrib>Khan, Colin</creatorcontrib><creatorcontrib>Hodson, Peter V.</creatorcontrib><creatorcontrib>Rice, Stanley D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aqualine</collection><collection>Ecology Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Pollution Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>ASFA: Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><jtitle>Marine environmental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Short, Jeffrey W.</au><au>Springman, Kathrine R.</au><au>Lindeberg, Mandy R.</au><au>Holland, Larry G.</au><au>Larsen, Marie L.</au><au>Sloan, Catherine A.</au><au>Khan, Colin</au><au>Hodson, Peter V.</au><au>Rice, Stanley D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Semipermeable membrane devices link site-specific contaminants to effects: PART II – A comparison of lingering Exxon Valdez oil with other potential sources of CYP1A inducers in Prince William Sound, Alaska</atitle><jtitle>Marine environmental research</jtitle><addtitle>Mar Environ Res</addtitle><date>2008-12-01</date><risdate>2008</risdate><volume>66</volume><issue>5</issue><spage>487</spage><epage>498</epage><pages>487-498</pages><issn>0141-1136</issn><eissn>1879-0291</eissn><abstract>We deployed semipermeable membrane devices (SPMDs) on beaches for 28 days at 53 sites in Prince William Sound (PWS), Alaska, to evaluate the induction potential from suspected sources of cytochrome P450 1A (CYP1A)-inducing contaminants. Sites were selected to assess known point sources, or were chosen randomly to evaluate the region-wide sources. After deployment, SPMD extracts were analyzed chemically for persistent organic pollutants (POPs) and polycyclic aromatic hydrocarbons (PAH). These results were compared with hepatic CYP1A enzyme activity of juvenile rainbow trout injected with the same extracts prior to clean-up for the chemical analyses. Increased CYP1A activity was strongly associated with PAH concentrations in extracts, especially chrysene homologues but was not associated with POPs. The only apparent sources of chrysene homologues were lingering oil from Exxon Valdez, asphalt and bunker fuels released from storage tanks during the 1964 Alaska earthquake, creosote leaching from numerous pilings at one site, and PAH-contaminated sediments at Cordova Harbor. Our results indicate that PWS is remarkably free of pollution from PAH when nearby sources are absent as well as from pesticides and PCBs generally.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>18845332</pmid><doi>10.1016/j.marenvres.2008.08.007</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Marine environmental research, 2008-12, Vol.66 (5), p.487-498 |
| issn | 0141-1136 1879-0291 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Alaska Animal and plant ecology Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences Biological Availability Cytochrome P-450 CYP1A1 - metabolism Ecotoxicology, biological effects of pollution Environmental Monitoring - instrumentation Environmental Monitoring - methods Enzyme Induction - drug effects Fundamental and applied biological sciences. Psychology Marine Oil spills Oncorhynchus mykiss Oncorhynchus mykiss - metabolism PAH PCB Petroleum Pollution monitoring Sea water ecosystems Sources SPMD Synecology Water Pollutants, Chemical - toxicity |
| title | Semipermeable membrane devices link site-specific contaminants to effects: PART II – A comparison of lingering Exxon Valdez oil with other potential sources of CYP1A inducers in Prince William Sound, Alaska |
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