Recurrent stroke after cervical artery dissection
ObjectiveCervical artery dissection (CAD) accounts for 10–20% of all strokes in young adults, but no randomised controlled trial has investigated the best secondary prevention after ischaemic stroke or transient ischaemic attack (TIA). Because only small numbers of patient with CAD have been prospec...
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| Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2010-08, Vol.81 (8), p.869-873 |
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| container_title | Journal of neurology, neurosurgery and psychiatry |
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| creator | Weimar, Christian Kraywinkel, Klaus Hagemeister, Christoph Haaß, Anton Katsarava, Zaza Brunner, Freimuth Haverkamp, Christian Schmid, Elisabeth Diener, Hans-Christoph |
| description | ObjectiveCervical artery dissection (CAD) accounts for 10–20% of all strokes in young adults, but no randomised controlled trial has investigated the best secondary prevention after ischaemic stroke or transient ischaemic attack (TIA). Because only small numbers of patient with CAD have been prospectively documented and followed up, the authors aimed to investigate the prognosis under various prevention regimens.Methods30 German departments of neurology with acute stroke units prospectively documented 250 patients with acute ischaemic stroke or TIA due to CAD. A central follow-up (median 31 months) assessed recurrent stroke, recurrent CAD and death in 198 patients.ResultsCAD was found more often in the carotid arteries (52.0%) than in the vertebral arteries (46.8%). Thirteen patients (5.2%, CI 3.1% to 8.6%) suffered a recurrent stroke during the acute hospital stay. The rate of recurrent CAD during the first year was 1.7% (95% CI 0.3% to 3.6%). The cumulative recurrent stroke rate during the first year was 10.7% (95% CI 6.5% to 14.9%) and 14.0% (95% CI 8.9% to 19.1%) over 3 years. After discharge, the rate of recurrent stroke up to 6 months in patients treated with anticoagulants was 2.0% (95% CI 0.6% to 7.1%) and in those treated with antiplatelets 16.7% (95% CI 5.8% to 39.2%), which was statistically significant (HR 0.11; CI 0.02 to 0.69, p=0.02).ConclusionsThis observational study confirms a high risk of early recurrent stroke following acute IS or TIA due to CAD. Whether anticoagulation provides any benefit over antiplatelets needs to be investigated in a randomised controlled trial. |
| doi_str_mv | 10.1136/jnnp.2009.192153 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_00562294v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>748943847</sourcerecordid><originalsourceid>FETCH-LOGICAL-b506t-5599780f4ef0d56e277cd2f651988910038e82a442ab4f3c133ed4e5421536e3</originalsourceid><addsrcrecordid>eNqFkN-L1DAQx4Mo3t7pu09SEDlEuk5-J4_nonfiorAc4lvIplPsXrddk_bw_ntTuq7gi3kJmXzmy8yHkBcUlpRy9W7XdYclA7BLahmV_BFZUKFMyTl8f0wWAIyVHCSckfOUdjAdY5-SMwbKME3tgtANhjFG7IYiDbG_w8LXA8YiYLxvgm8LH_PzoaialDAMTd89I09q3yZ8frwvyO3HD7erm3L99frT6mpdbiWooZTSWm2gFlhDJRUyrUPFaiWpNcZSAG7QMC8E81tR80A5x0qgFNMeCvkFeTPH_vCtO8Rm7-OD633jbq7WbqoBSMWYFfc0s5cze4j9zxHT4PZNCti2vsN-TE4LYwU3Qmfy1T_krh9jl_dwVBvKhBTGZApmKsQ-pYj1aQAKbhLvJvFuEu9m8bnl5TF43O6xOjX8MZ2B10fAp-y1jr4LTfrLcTBKWchcOXNNGvDX6d_HO6c019J9-bZyaqPeX28-czflvp357X73_zF_A3nOpOs</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1781245488</pqid></control><display><type>article</type><title>Recurrent stroke after cervical artery dissection</title><source>MEDLINE</source><source>BMJ Journals - NESLi2</source><creator>Weimar, Christian ; Kraywinkel, Klaus ; Hagemeister, Christoph ; Haaß, Anton ; Katsarava, Zaza ; Brunner, Freimuth ; Haverkamp, Christian ; Schmid, Elisabeth ; Diener, Hans-Christoph</creator><creatorcontrib>Weimar, Christian ; Kraywinkel, Klaus ; Hagemeister, Christoph ; Haaß, Anton ; Katsarava, Zaza ; Brunner, Freimuth ; Haverkamp, Christian ; Schmid, Elisabeth ; Diener, Hans-Christoph ; German Stroke Study Collaboration ; on behalf of the German Stroke Study Collaboration</creatorcontrib><description>ObjectiveCervical artery dissection (CAD) accounts for 10–20% of all strokes in young adults, but no randomised controlled trial has investigated the best secondary prevention after ischaemic stroke or transient ischaemic attack (TIA). Because only small numbers of patient with CAD have been prospectively documented and followed up, the authors aimed to investigate the prognosis under various prevention regimens.Methods30 German departments of neurology with acute stroke units prospectively documented 250 patients with acute ischaemic stroke or TIA due to CAD. A central follow-up (median 31 months) assessed recurrent stroke, recurrent CAD and death in 198 patients.ResultsCAD was found more often in the carotid arteries (52.0%) than in the vertebral arteries (46.8%). Thirteen patients (5.2%, CI 3.1% to 8.6%) suffered a recurrent stroke during the acute hospital stay. The rate of recurrent CAD during the first year was 1.7% (95% CI 0.3% to 3.6%). The cumulative recurrent stroke rate during the first year was 10.7% (95% CI 6.5% to 14.9%) and 14.0% (95% CI 8.9% to 19.1%) over 3 years. After discharge, the rate of recurrent stroke up to 6 months in patients treated with anticoagulants was 2.0% (95% CI 0.6% to 7.1%) and in those treated with antiplatelets 16.7% (95% CI 5.8% to 39.2%), which was statistically significant (HR 0.11; CI 0.02 to 0.69, p=0.02).ConclusionsThis observational study confirms a high risk of early recurrent stroke following acute IS or TIA due to CAD. Whether anticoagulation provides any benefit over antiplatelets needs to be investigated in a randomised controlled trial.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.2009.192153</identifier><identifier>PMID: 20682719</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Adult ; Age ; Anticoagulants ; Anticoagulants - therapeutic use ; arterial dissection ; Biological and medical sciences ; Cardiovascular disease ; Carotid arteries ; Cerebral Arterial Diseases - complications ; Cerebral Arterial Diseases - pathology ; Cohort Studies ; Dissection ; Female ; Fibrinolytic Agents - therapeutic use ; Follow-Up Studies ; Germany ; Humans ; Ischemic Attack, Transient - etiology ; Ischemic Attack, Transient - pathology ; Kaplan-Meier Estimate ; long-term prognosis ; Male ; Medical imaging ; Medical prognosis ; Medical sciences ; Middle Aged ; Neurology ; Platelet Aggregation Inhibitors - therapeutic use ; Prognosis ; Prospective Studies ; Recurrence ; Risk Factors ; Stroke ; Stroke - etiology ; Stroke - pathology ; Studies ; Survival ; Ultrasonic imaging ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 2010-08, Vol.81 (8), p.869-873</ispartof><rights>2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright: 2010 (c) 2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b506t-5599780f4ef0d56e277cd2f651988910038e82a442ab4f3c133ed4e5421536e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jnnp.bmj.com/content/81/8/869.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://jnnp.bmj.com/content/81/8/869.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,776,780,881,3183,23552,27903,27904,77346,77377</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23086690$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20682719$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00562294$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Weimar, Christian</creatorcontrib><creatorcontrib>Kraywinkel, Klaus</creatorcontrib><creatorcontrib>Hagemeister, Christoph</creatorcontrib><creatorcontrib>Haaß, Anton</creatorcontrib><creatorcontrib>Katsarava, Zaza</creatorcontrib><creatorcontrib>Brunner, Freimuth</creatorcontrib><creatorcontrib>Haverkamp, Christian</creatorcontrib><creatorcontrib>Schmid, Elisabeth</creatorcontrib><creatorcontrib>Diener, Hans-Christoph</creatorcontrib><creatorcontrib>German Stroke Study Collaboration</creatorcontrib><creatorcontrib>on behalf of the German Stroke Study Collaboration</creatorcontrib><title>Recurrent stroke after cervical artery dissection</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>ObjectiveCervical artery dissection (CAD) accounts for 10–20% of all strokes in young adults, but no randomised controlled trial has investigated the best secondary prevention after ischaemic stroke or transient ischaemic attack (TIA). Because only small numbers of patient with CAD have been prospectively documented and followed up, the authors aimed to investigate the prognosis under various prevention regimens.Methods30 German departments of neurology with acute stroke units prospectively documented 250 patients with acute ischaemic stroke or TIA due to CAD. A central follow-up (median 31 months) assessed recurrent stroke, recurrent CAD and death in 198 patients.ResultsCAD was found more often in the carotid arteries (52.0%) than in the vertebral arteries (46.8%). Thirteen patients (5.2%, CI 3.1% to 8.6%) suffered a recurrent stroke during the acute hospital stay. The rate of recurrent CAD during the first year was 1.7% (95% CI 0.3% to 3.6%). The cumulative recurrent stroke rate during the first year was 10.7% (95% CI 6.5% to 14.9%) and 14.0% (95% CI 8.9% to 19.1%) over 3 years. After discharge, the rate of recurrent stroke up to 6 months in patients treated with anticoagulants was 2.0% (95% CI 0.6% to 7.1%) and in those treated with antiplatelets 16.7% (95% CI 5.8% to 39.2%), which was statistically significant (HR 0.11; CI 0.02 to 0.69, p=0.02).ConclusionsThis observational study confirms a high risk of early recurrent stroke following acute IS or TIA due to CAD. Whether anticoagulation provides any benefit over antiplatelets needs to be investigated in a randomised controlled trial.</description><subject>Adult</subject><subject>Age</subject><subject>Anticoagulants</subject><subject>Anticoagulants - therapeutic use</subject><subject>arterial dissection</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular disease</subject><subject>Carotid arteries</subject><subject>Cerebral Arterial Diseases - complications</subject><subject>Cerebral Arterial Diseases - pathology</subject><subject>Cohort Studies</subject><subject>Dissection</subject><subject>Female</subject><subject>Fibrinolytic Agents - therapeutic use</subject><subject>Follow-Up Studies</subject><subject>Germany</subject><subject>Humans</subject><subject>Ischemic Attack, Transient - etiology</subject><subject>Ischemic Attack, Transient - pathology</subject><subject>Kaplan-Meier Estimate</subject><subject>long-term prognosis</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medical prognosis</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Stroke</subject><subject>Stroke - etiology</subject><subject>Stroke - pathology</subject><subject>Studies</subject><subject>Survival</subject><subject>Ultrasonic imaging</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0022-3050</issn><issn>1468-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkN-L1DAQx4Mo3t7pu09SEDlEuk5-J4_nonfiorAc4lvIplPsXrddk_bw_ntTuq7gi3kJmXzmy8yHkBcUlpRy9W7XdYclA7BLahmV_BFZUKFMyTl8f0wWAIyVHCSckfOUdjAdY5-SMwbKME3tgtANhjFG7IYiDbG_w8LXA8YiYLxvgm8LH_PzoaialDAMTd89I09q3yZ8frwvyO3HD7erm3L99frT6mpdbiWooZTSWm2gFlhDJRUyrUPFaiWpNcZSAG7QMC8E81tR80A5x0qgFNMeCvkFeTPH_vCtO8Rm7-OD633jbq7WbqoBSMWYFfc0s5cze4j9zxHT4PZNCti2vsN-TE4LYwU3Qmfy1T_krh9jl_dwVBvKhBTGZApmKsQ-pYj1aQAKbhLvJvFuEu9m8bnl5TF43O6xOjX8MZ2B10fAp-y1jr4LTfrLcTBKWchcOXNNGvDX6d_HO6c019J9-bZyaqPeX28-czflvp357X73_zF_A3nOpOs</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Weimar, Christian</creator><creator>Kraywinkel, Klaus</creator><creator>Hagemeister, Christoph</creator><creator>Haaß, Anton</creator><creator>Katsarava, Zaza</creator><creator>Brunner, Freimuth</creator><creator>Haverkamp, Christian</creator><creator>Schmid, Elisabeth</creator><creator>Diener, Hans-Christoph</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope></search><sort><creationdate>20100801</creationdate><title>Recurrent stroke after cervical artery dissection</title><author>Weimar, Christian ; Kraywinkel, Klaus ; Hagemeister, Christoph ; Haaß, Anton ; Katsarava, Zaza ; Brunner, Freimuth ; Haverkamp, Christian ; Schmid, Elisabeth ; Diener, Hans-Christoph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b506t-5599780f4ef0d56e277cd2f651988910038e82a442ab4f3c133ed4e5421536e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Age</topic><topic>Anticoagulants</topic><topic>Anticoagulants - therapeutic use</topic><topic>arterial dissection</topic><topic>Biological and medical sciences</topic><topic>Cardiovascular disease</topic><topic>Carotid arteries</topic><topic>Cerebral Arterial Diseases - complications</topic><topic>Cerebral Arterial Diseases - pathology</topic><topic>Cohort Studies</topic><topic>Dissection</topic><topic>Female</topic><topic>Fibrinolytic Agents - therapeutic use</topic><topic>Follow-Up Studies</topic><topic>Germany</topic><topic>Humans</topic><topic>Ischemic Attack, Transient - etiology</topic><topic>Ischemic Attack, Transient - pathology</topic><topic>Kaplan-Meier Estimate</topic><topic>long-term prognosis</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medical prognosis</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Platelet Aggregation Inhibitors - therapeutic use</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Recurrence</topic><topic>Risk Factors</topic><topic>Stroke</topic><topic>Stroke - etiology</topic><topic>Stroke - pathology</topic><topic>Studies</topic><topic>Survival</topic><topic>Ultrasonic imaging</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weimar, Christian</creatorcontrib><creatorcontrib>Kraywinkel, Klaus</creatorcontrib><creatorcontrib>Hagemeister, Christoph</creatorcontrib><creatorcontrib>Haaß, Anton</creatorcontrib><creatorcontrib>Katsarava, Zaza</creatorcontrib><creatorcontrib>Brunner, Freimuth</creatorcontrib><creatorcontrib>Haverkamp, Christian</creatorcontrib><creatorcontrib>Schmid, Elisabeth</creatorcontrib><creatorcontrib>Diener, Hans-Christoph</creatorcontrib><creatorcontrib>German Stroke Study Collaboration</creatorcontrib><creatorcontrib>on behalf of the German Stroke Study Collaboration</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weimar, Christian</au><au>Kraywinkel, Klaus</au><au>Hagemeister, Christoph</au><au>Haaß, Anton</au><au>Katsarava, Zaza</au><au>Brunner, Freimuth</au><au>Haverkamp, Christian</au><au>Schmid, Elisabeth</au><au>Diener, Hans-Christoph</au><aucorp>German Stroke Study Collaboration</aucorp><aucorp>on behalf of the German Stroke Study Collaboration</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recurrent stroke after cervical artery dissection</atitle><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle><addtitle>J Neurol Neurosurg Psychiatry</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>81</volume><issue>8</issue><spage>869</spage><epage>873</epage><pages>869-873</pages><issn>0022-3050</issn><eissn>1468-330X</eissn><coden>JNNPAU</coden><abstract>ObjectiveCervical artery dissection (CAD) accounts for 10–20% of all strokes in young adults, but no randomised controlled trial has investigated the best secondary prevention after ischaemic stroke or transient ischaemic attack (TIA). Because only small numbers of patient with CAD have been prospectively documented and followed up, the authors aimed to investigate the prognosis under various prevention regimens.Methods30 German departments of neurology with acute stroke units prospectively documented 250 patients with acute ischaemic stroke or TIA due to CAD. A central follow-up (median 31 months) assessed recurrent stroke, recurrent CAD and death in 198 patients.ResultsCAD was found more often in the carotid arteries (52.0%) than in the vertebral arteries (46.8%). Thirteen patients (5.2%, CI 3.1% to 8.6%) suffered a recurrent stroke during the acute hospital stay. The rate of recurrent CAD during the first year was 1.7% (95% CI 0.3% to 3.6%). The cumulative recurrent stroke rate during the first year was 10.7% (95% CI 6.5% to 14.9%) and 14.0% (95% CI 8.9% to 19.1%) over 3 years. After discharge, the rate of recurrent stroke up to 6 months in patients treated with anticoagulants was 2.0% (95% CI 0.6% to 7.1%) and in those treated with antiplatelets 16.7% (95% CI 5.8% to 39.2%), which was statistically significant (HR 0.11; CI 0.02 to 0.69, p=0.02).ConclusionsThis observational study confirms a high risk of early recurrent stroke following acute IS or TIA due to CAD. Whether anticoagulation provides any benefit over antiplatelets needs to be investigated in a randomised controlled trial.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>20682719</pmid><doi>10.1136/jnnp.2009.192153</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Age Anticoagulants Anticoagulants - therapeutic use arterial dissection Biological and medical sciences Cardiovascular disease Carotid arteries Cerebral Arterial Diseases - complications Cerebral Arterial Diseases - pathology Cohort Studies Dissection Female Fibrinolytic Agents - therapeutic use Follow-Up Studies Germany Humans Ischemic Attack, Transient - etiology Ischemic Attack, Transient - pathology Kaplan-Meier Estimate long-term prognosis Male Medical imaging Medical prognosis Medical sciences Middle Aged Neurology Platelet Aggregation Inhibitors - therapeutic use Prognosis Prospective Studies Recurrence Risk Factors Stroke Stroke - etiology Stroke - pathology Studies Survival Ultrasonic imaging Vascular diseases and vascular malformations of the nervous system |
| title | Recurrent stroke after cervical artery dissection |
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