MALDI-TOF-MS for rapid detection of staphylococcal Panton–Valentine leukocidin

Abstract Toxin-producing Gram-positive bacteria are responsible for emerging and life-threatening infections in humans worldwide. Both rapid toxin detection and adapted therapy are essential to limit the morbidity due to such toxins, especially staphylococcal Panton–Valentine leukocidin (PVL). Here...

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Veröffentlicht in:	International journal of antimicrobial agents 2009-11, Vol.34 (5), p.467-470
Hauptverfasser:	Bittar, Fadi, Ouchenane, Zoulikha, Smati, Farida, Raoult, Didier, Rolain, Jean-Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial diseases Bacterial Toxins - analysis Biological and medical sciences Exotoxins - analysis Human bacterial diseases Humans Infectious Disease Infectious diseases Leukocidins - analysis Medical sciences Pharmacology. Drug treatments Sensitivity and Specificity Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Staphylococcal Infections - microbiology Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Staphylococcus aureus - chemistry Staphylococcus aureus - isolation & purification Time Factors Virulence Factors - analysis
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