Frequency and phenotype of SPG11 and SPG15 in complicated spastic paraplegia (HSP)

Background: Hereditary spastic paraplegias (HSP) are clinically and genetically highly heterogeneous. Recently two novel genes, SPG11(spatacsin) and SPG15 (spastizin), associated with autosomal recessive HSP (AR-HSP) were identified. Clinically, both are characterized by complicated HSP and a rather...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2009-11, Vol.80 (12)
Hauptverfasser:	Schüle, Rebecca, Schlipf, Nina, Synofzik, Matthis, Klebe, Stefan, Klimpe, Sven, Hehr, Ute, Winner, Beate, Lindig, Tobias, Dotzer, Andrea, Riess, Olaf, Winkler, Jürgen, Schöls, Ludger, Bauer, Peter
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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