Estrogen receptor subtype-specific effects on markers of bone homeostasis

To further elucidate the processes involved in the physiology of bone-protection by estrogens, ovariectomized (OVX) rats were treated subcutaneously with 17β-estradiol (E 2), the ERα-specific agonist (16α-LE2) and the ERβ-specific agonist (8β-VE2). OVX and intact animals served as controls. Biomarke...

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Veröffentlicht in:	Molecular and cellular endocrinology 2008-09, Vol.291 (1), p.104-108
Hauptverfasser:	Hertrampf, T., Schleipen, B., Velders, M., Laudenbach, U., Fritzemeier, K.H., Diel, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemical bone markers Biomarkers - metabolism Bone and Bones - metabolism Bone Density Bone mineral density Estradiol - metabolism Estrogen receptor alpha Estrogen Receptor alpha - agonists Estrogen Receptor alpha - genetics Estrogen Receptor alpha - metabolism Estrogen receptor beta Estrogen Receptor beta - agonists Estrogen Receptor beta - genetics Estrogen Receptor beta - metabolism Estrogen receptor subtype-specific agonists estrogens Female Homeostasis Molecular Structure Organ Size Ovariectomy Random Allocation Rats Uterus - anatomy & histology Uterus - metabolism
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