Molecular basis of the myogenic profile of aged human skeletal muscle satellite cells during differentiation

Sarcopenia is the age-related loss of muscle mass, strength and function. Human muscle proteins are synthesized at a slower rate in the elderly than in young adults, leading to atrophy and muscle mass loss with a decline in the functional capability. Additionally, aging is accompanied by a decrease...

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Veröffentlicht in:Experimental gerontology 2009-08, Vol.44 (8), p.523-531
Hauptverfasser: Pietrangelo, Tiziana, Puglielli, Cristina, Mancinelli, Rosa, Beccafico, Sara, Fanò, Giorgio, Fulle, Stefania
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Sprache:eng
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