Characterization of human and bovine phosphatidylethanolamine-binding protein (PEBP/RKIP) interactions with morphine and morphine-glucuronides determined by noncovalent mass spectrometry

The phosphatidylethanolamine-binding protein (PEBP/RKIP), initially found to bind phosphatidylethanolamine (PE), has been shown to be associated with morphine derivatives. Our recent study on bovine primary chromaffin cells showed that inside secretory granules, PEBP is noncovalently associated to e...

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Veröffentlicht in:	Medical science monitor 2009-07, Vol.15 (7), p.BR178-BR187
Hauptverfasser:	Atmanene, Cédric, Laux, Alexis, Glattard, Elise, Muller, Arnaud, Schoentgen, Françoise, Metz-Boutigue, Marie-Hélène, Aunis, Dominique, Van Dorsselaer, Alain, Stefano, George B, Sanglier-Cianférani, Sarah, Goumon, Yannick
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry, Molecular Biology Cattle Humans Life Sciences Mass Spectrometry Morphine Derivatives - chemistry Morphine Derivatives - metabolism Phosphatidylethanolamine Binding Protein - metabolism Phosphatidylethanolamines - metabolism Titrimetry
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