Glycyrrhizin, the main active compound in licorice, attenuates pro-inflammatory responses by interfering with membrane-dependent receptor signaling

The triterpene glycoside glycyrrhizin (GL) is the main active compound in licorice. It is used as a herbal medicine owing to its anti-cancer, anti-viral, and anti-inflammatory properties. Its mode of action however remains widely unknown. In this study, we aimed to elucidate the molecular mechanism...

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Veröffentlicht in:Biochemical journal 2009-07, Vol.421 (3), p.473-482
Hauptverfasser: Schröfelbauer, Bärbel, Raffetseder, Johanna, Hauner, Maria, Wolkerstorfer, Andrea, Ernst, Wolfgang E., Szolar, Oliver H. J.
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Sprache:eng
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