Severe bacterial keratitis and activity of fluoroquinolones
To study the microbiological characteristics of patients with severe bacterial keratitis in Bordeaux, France, as well as the species' resistance to fluoroquinolones. We conducted a retrospective study of 57 patients presenting severe bacterial keratitis over 20 months. The positive bacteriologi...
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Veröffentlicht in: | Journal francais d'ophtalmologie 2009-04, Vol.32 (4), p.273-276 |
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creator | Mesplié, N Kérautret, J Léoni, S Dubois, V Colin, J |
description | To study the microbiological characteristics of patients with severe bacterial keratitis in Bordeaux, France, as well as the species' resistance to fluoroquinolones.
We conducted a retrospective study of 57 patients presenting severe bacterial keratitis over 20 months. The positive bacteriological cultures of the corneal smears, bacteria, and the antibiogram were listed.
Fifty-seven patients with severe bacterial keratitis were hospitalized from March 2005 to November 2006. Pseudomonas aeruginosa (n=17), Staphylococcus aureus (n=16), and coagulase-negative Staphylococcus (n=10) were the most frequent species. P. aeruginosa was sensitive in 100% of cases to ciprofloxacin, S. aureus was sensitive in 94% of cases to ciprofloxacin, and coagulase-negative Staphylococcus species were sensitive in 100% of cases to ciprofloxacin. No significant different was noted between ciprofloxacin, levofloxacin, and moxifloxacin on the bacteria studied (p>0.05).
In this study, except for the Streptococcus species, ciprofloxacin was effective against the species responsible for severe bacterial keratitis. |
doi_str_mv | 10.1016/j.jfo.2008.12.002 |
format | Article |
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We conducted a retrospective study of 57 patients presenting severe bacterial keratitis over 20 months. The positive bacteriological cultures of the corneal smears, bacteria, and the antibiogram were listed.
Fifty-seven patients with severe bacterial keratitis were hospitalized from March 2005 to November 2006. Pseudomonas aeruginosa (n=17), Staphylococcus aureus (n=16), and coagulase-negative Staphylococcus (n=10) were the most frequent species. P. aeruginosa was sensitive in 100% of cases to ciprofloxacin, S. aureus was sensitive in 94% of cases to ciprofloxacin, and coagulase-negative Staphylococcus species were sensitive in 100% of cases to ciprofloxacin. No significant different was noted between ciprofloxacin, levofloxacin, and moxifloxacin on the bacteria studied (p>0.05).
In this study, except for the Streptococcus species, ciprofloxacin was effective against the species responsible for severe bacterial keratitis.</description><identifier>ISSN: 0181-5512</identifier><identifier>EISSN: 1773-0597</identifier><identifier>DOI: 10.1016/j.jfo.2008.12.002</identifier><identifier>PMID: 19515343</identifier><language>fre</language><publisher>France: Elsevier Masson</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents - pharmacology ; Bacteria - drug effects ; Child ; Child, Preschool ; Fluoroquinolones - pharmacology ; Humans ; Infant ; Keratitis - microbiology ; Life Sciences ; Microbial Sensitivity Tests ; Microbiology and Parasitology ; Middle Aged ; Retrospective Studies ; Severity of Illness Index ; Young Adult</subject><ispartof>Journal francais d'ophtalmologie, 2009-04, Vol.32 (4), p.273-276</ispartof><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19515343$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00426331$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Mesplié, N</creatorcontrib><creatorcontrib>Kérautret, J</creatorcontrib><creatorcontrib>Léoni, S</creatorcontrib><creatorcontrib>Dubois, V</creatorcontrib><creatorcontrib>Colin, J</creatorcontrib><title>Severe bacterial keratitis and activity of fluoroquinolones</title><title>Journal francais d'ophtalmologie</title><addtitle>J Fr Ophtalmol</addtitle><description>To study the microbiological characteristics of patients with severe bacterial keratitis in Bordeaux, France, as well as the species' resistance to fluoroquinolones.
We conducted a retrospective study of 57 patients presenting severe bacterial keratitis over 20 months. The positive bacteriological cultures of the corneal smears, bacteria, and the antibiogram were listed.
Fifty-seven patients with severe bacterial keratitis were hospitalized from March 2005 to November 2006. Pseudomonas aeruginosa (n=17), Staphylococcus aureus (n=16), and coagulase-negative Staphylococcus (n=10) were the most frequent species. P. aeruginosa was sensitive in 100% of cases to ciprofloxacin, S. aureus was sensitive in 94% of cases to ciprofloxacin, and coagulase-negative Staphylococcus species were sensitive in 100% of cases to ciprofloxacin. No significant different was noted between ciprofloxacin, levofloxacin, and moxifloxacin on the bacteria studied (p>0.05).
In this study, except for the Streptococcus species, ciprofloxacin was effective against the species responsible for severe bacterial keratitis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Bacteria - drug effects</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Fluoroquinolones - pharmacology</subject><subject>Humans</subject><subject>Infant</subject><subject>Keratitis - microbiology</subject><subject>Life Sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Microbiology and Parasitology</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>Young Adult</subject><issn>0181-5512</issn><issn>1773-0597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE9Lw0AQRxdRbKn9AF4kN_GQOLN_slk8laJWKHhQz2HTzNKtabdmk0K_vS2tngYej8ePYewWIUPA_HGVrVzIOECRIc8A-AUbotYiBWX0JRsCFpgqhXzAxjH6CtDkXB_ANRugUaiEFEP29EE7aimp7KKj1tsm-abWdr7zMbGbOjlgv_PdPgkucU0f2vDT-01owobiDbtytok0Pt8R-3p5_pzO0vn769t0Mk-XqGWXchBcKiKSpjAWqlorbnilyRqHwtXKCakcYp0LrUFUSEWRG2OloYqwVmLEHk7dpW3KbevXtt2XwfpyNpmXRwYgeS4E7vDg3p_c7XEpxa5c-7igprEbCn0stZBcyAKO1buz2Vdrqv_Df78Rv5ooZkU</recordid><startdate>200904</startdate><enddate>200904</enddate><creator>Mesplié, N</creator><creator>Kérautret, J</creator><creator>Léoni, S</creator><creator>Dubois, V</creator><creator>Colin, J</creator><general>Elsevier Masson</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>200904</creationdate><title>Severe bacterial keratitis and activity of fluoroquinolones</title><author>Mesplié, N ; Kérautret, J ; Léoni, S ; Dubois, V ; Colin, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h174t-203245eee4989a0bd75292b7ea9f13fd5f345f11d637703b1e88699a49ebe1d53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Bacteria - drug effects</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Fluoroquinolones - pharmacology</topic><topic>Humans</topic><topic>Infant</topic><topic>Keratitis - microbiology</topic><topic>Life Sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Microbiology and Parasitology</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mesplié, N</creatorcontrib><creatorcontrib>Kérautret, J</creatorcontrib><creatorcontrib>Léoni, S</creatorcontrib><creatorcontrib>Dubois, V</creatorcontrib><creatorcontrib>Colin, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Journal francais d'ophtalmologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mesplié, N</au><au>Kérautret, J</au><au>Léoni, S</au><au>Dubois, V</au><au>Colin, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Severe bacterial keratitis and activity of fluoroquinolones</atitle><jtitle>Journal francais d'ophtalmologie</jtitle><addtitle>J Fr Ophtalmol</addtitle><date>2009-04</date><risdate>2009</risdate><volume>32</volume><issue>4</issue><spage>273</spage><epage>276</epage><pages>273-276</pages><issn>0181-5512</issn><eissn>1773-0597</eissn><abstract>To study the microbiological characteristics of patients with severe bacterial keratitis in Bordeaux, France, as well as the species' resistance to fluoroquinolones.
We conducted a retrospective study of 57 patients presenting severe bacterial keratitis over 20 months. The positive bacteriological cultures of the corneal smears, bacteria, and the antibiogram were listed.
Fifty-seven patients with severe bacterial keratitis were hospitalized from March 2005 to November 2006. Pseudomonas aeruginosa (n=17), Staphylococcus aureus (n=16), and coagulase-negative Staphylococcus (n=10) were the most frequent species. P. aeruginosa was sensitive in 100% of cases to ciprofloxacin, S. aureus was sensitive in 94% of cases to ciprofloxacin, and coagulase-negative Staphylococcus species were sensitive in 100% of cases to ciprofloxacin. No significant different was noted between ciprofloxacin, levofloxacin, and moxifloxacin on the bacteria studied (p>0.05).
In this study, except for the Streptococcus species, ciprofloxacin was effective against the species responsible for severe bacterial keratitis.</abstract><cop>France</cop><pub>Elsevier Masson</pub><pmid>19515343</pmid><doi>10.1016/j.jfo.2008.12.002</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present); Alma/SFX Local Collection |
subjects | Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Bacteria - drug effects Child Child, Preschool Fluoroquinolones - pharmacology Humans Infant Keratitis - microbiology Life Sciences Microbial Sensitivity Tests Microbiology and Parasitology Middle Aged Retrospective Studies Severity of Illness Index Young Adult |
title | Severe bacterial keratitis and activity of fluoroquinolones |
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