DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

All under control: The programmability of hybridization has been utilized to generate a combinatorial library of structures that emulate the topologies of complex carbohydrates interacting with an antibody that shows broad‐spectrum activity against HIV. This simple method involves attaching oligosac...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 2009-01, Vol.48 (41), p.7695-7700
Hauptverfasser:	Gorska, Katarzyna, Huang, Kuo-Ting, Chaloin, Olivier, Winssinger, Nicolas
Format:	Artikel
Sprache:	eng
Schlagworte:	bioorganic chemistry Carbohydrate Conformation Carbohydrate Sequence carbohydrates Chemical Sciences Dimerization DNA DNA - chemistry DNA - genetics Epitopes - chemistry HIV HIV - chemistry HIV - immunology Human immunodeficiency virus Molecular Sequence Data Oligosaccharides - chemistry Organic chemistry peptide nucleic acids Peptide Nucleic Acids - chemistry Peptide Nucleic Acids - genetics
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