Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair?

Recent studies have identified a new population of interleukin-22-producing cells in mucosal tissues that share features with both lymphoid-tissue inducer cells and natural killer cells. How are these three cell populations related and what might be the function of the new cell population? Mucosal t...

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Veröffentlicht in:	Nature reviews. Immunology 2009-04, Vol.9 (4), p.229-234
Hauptverfasser:	Vivier, Eric, Cupedo, Tom, Spits, Hergen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cell Lineage Chemokines Cytokines Embryos Genetic aspects Health aspects Humans Immunity Immunity, Innate Immunity, Innate - immunology Immunity, Mucosal Immunity, Mucosal - immunology Immunology Interleukin-22 Interleukins Interleukins - biosynthesis Intestinal Mucosa Intestinal Mucosa - cytology Intestinal Mucosa - physiology Killer cells Killer Cells, Natural Killer Cells, Natural - cytology Killer Cells, Natural - physiology Life Sciences Lymph nodes Lymphatic system Lymphocytes Lymphocytes - cytology Lymphocytes - immunology Lymphocytes - metabolism Lymphocytes - physiology Lymphoid Progenitor Cells Lymphoid Progenitor Cells - cytology Lymphoid Progenitor Cells - physiology Lymphoid tissue Mice Models, Biological Palatine Tonsil Palatine Tonsil - cytology Palatine Tonsil - physiology Physiological aspects progress Proteins Regeneration Regeneration - physiology Tissues Tumor necrosis factor-TNF
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