Alpha-linolenic acid and coronary heart disease
Abstract To summarize our present knowledge about vegetable omega-3 fatty acids. Alpha-linolenic acid (ALA) is one of the two essential fatty acids in humans. Epidemiological studies and dietary trials strongly suggest that this fatty acid is important in relation with the pathogenesis (and preventi...
Gespeichert in:
| Veröffentlicht in: | Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2004-06, Vol.14 (3), p.162-169 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 169 |
|---|---|
| container_issue | 3 |
| container_start_page | 162 |
| container_title | Nutrition, metabolism, and cardiovascular diseases |
| container_volume | 14 |
| creator | de Lorgeril, M. Salen, P. |
| description | Abstract
To summarize our present knowledge about vegetable omega-3 fatty acids.
Alpha-linolenic acid (ALA) is one of the two essential fatty acids in humans. Epidemiological studies and dietary trials strongly suggest that this fatty acid is important in relation with the pathogenesis (and prevention) of coronary heart disease. Like other n-3 fatty acids from marine origin, it may prevent cardiac arrhythmias and sudden cardiac death. The optimal dietary intake of alpha-linolenic acid seems to be about 2 g
per day or 0.6 to 1% of total energy intake. Obtaining an optimal ratio of the two essential fatty acids, linoleic and alpha-linolenic acids —
ie a ratio of less than 4 to 1 in the diet — is a major issue. The main sources of alpha-linolenic acid for the European population should be canola oil (and canola-oil based margarine if available), nuts (English walnut), ground linseeds and green leafy vegetables such as purslane.
Epidemiological studies and dietary trials in humans suggest that alpha-linolenic acid is a major cardioprotective nutrient. |
| doi_str_mv | 10.1016/S0939-4753(04)80037-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_00395347v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0939475304800371</els_id><sourcerecordid>66816670</sourcerecordid><originalsourceid>FETCH-LOGICAL-c447t-776357b381b4b73d7c14d9257a82907343b451bdf7daab97a465f3b3762ca59e3</originalsourceid><addsrcrecordid>eNqFkE1LAzEQhoMoWqs_QdmT2MPaZPO1OUkpaoWCB_Uc8rU0st3UZFvw37vbLfXoaWB4Zt6ZB4AbBB8QRGz6DgUWOeEU30MyKSHEPEcnYISogDnmhTgFoyNyAS5T-uoZiMk5uEAUY1hwNgLTWb1Zqbz2Tahd402mjLeZamxmQgyNij_ZyqnYZtYnp5K7AmeVqpO7PtQx-Hx--pgv8uXby-t8tswNIbzNOWeYco1LpInm2HKDiBUF5aosBOSYYE0o0rbiViktuCKMVlhjzgqjqHB4DCbD3pWq5Sb6dXeJDMrLxWwp-173jKCY8B3q2LuB3cTwvXWplWufjKtr1biwTZKxEjHWvT4GdABNDClFVx03Iyh7q3JvVfbKJCRyb1X2AbeHgK1eO_s3ddDYAY8D4DolO--iTMa7xjjrozOttMH_E_ELN9OEBA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66816670</pqid></control><display><type>article</type><title>Alpha-linolenic acid and coronary heart disease</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>de Lorgeril, M. ; Salen, P.</creator><creatorcontrib>de Lorgeril, M. ; Salen, P.</creatorcontrib><description>Abstract
To summarize our present knowledge about vegetable omega-3 fatty acids.
Alpha-linolenic acid (ALA) is one of the two essential fatty acids in humans. Epidemiological studies and dietary trials strongly suggest that this fatty acid is important in relation with the pathogenesis (and prevention) of coronary heart disease. Like other n-3 fatty acids from marine origin, it may prevent cardiac arrhythmias and sudden cardiac death. The optimal dietary intake of alpha-linolenic acid seems to be about 2 g
per day or 0.6 to 1% of total energy intake. Obtaining an optimal ratio of the two essential fatty acids, linoleic and alpha-linolenic acids —
ie a ratio of less than 4 to 1 in the diet — is a major issue. The main sources of alpha-linolenic acid for the European population should be canola oil (and canola-oil based margarine if available), nuts (English walnut), ground linseeds and green leafy vegetables such as purslane.
Epidemiological studies and dietary trials in humans suggest that alpha-linolenic acid is a major cardioprotective nutrient.</description><identifier>ISSN: 0939-4753</identifier><identifier>EISSN: 1590-3729</identifier><identifier>DOI: 10.1016/S0939-4753(04)80037-1</identifier><identifier>PMID: 15330276</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>alpha-Linolenic Acid ; alpha-Linolenic Acid - metabolism ; alpha-Linolenic Acid - therapeutic use ; Biological Markers ; Biomarkers - blood ; canola oil ; Cardiovascular Diseases ; Cardiovascular Diseases - prevention & control ; Coronary Artery Disease ; Coronary Artery Disease - metabolism ; Coronary Artery Disease - prevention & control ; Diet ; Dietary Supplements ; essential fatty acid ; Female ; Food and Nutrition ; Humans ; Life Sciences ; Male ; myocardial infarction ; Prognosis ; purslane ; Sensitivity and Specificity ; walnut</subject><ispartof>Nutrition, metabolism, and cardiovascular diseases, 2004-06, Vol.14 (3), p.162-169</ispartof><rights>2004 Elsevier Science</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c447t-776357b381b4b73d7c14d9257a82907343b451bdf7daab97a465f3b3762ca59e3</citedby><cites>FETCH-LOGICAL-c447t-776357b381b4b73d7c14d9257a82907343b451bdf7daab97a465f3b3762ca59e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0939475304800371$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15330276$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00395347$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>de Lorgeril, M.</creatorcontrib><creatorcontrib>Salen, P.</creatorcontrib><title>Alpha-linolenic acid and coronary heart disease</title><title>Nutrition, metabolism, and cardiovascular diseases</title><addtitle>Nutr Metab Cardiovasc Dis</addtitle><description>Abstract
To summarize our present knowledge about vegetable omega-3 fatty acids.
Alpha-linolenic acid (ALA) is one of the two essential fatty acids in humans. Epidemiological studies and dietary trials strongly suggest that this fatty acid is important in relation with the pathogenesis (and prevention) of coronary heart disease. Like other n-3 fatty acids from marine origin, it may prevent cardiac arrhythmias and sudden cardiac death. The optimal dietary intake of alpha-linolenic acid seems to be about 2 g
per day or 0.6 to 1% of total energy intake. Obtaining an optimal ratio of the two essential fatty acids, linoleic and alpha-linolenic acids —
ie a ratio of less than 4 to 1 in the diet — is a major issue. The main sources of alpha-linolenic acid for the European population should be canola oil (and canola-oil based margarine if available), nuts (English walnut), ground linseeds and green leafy vegetables such as purslane.
Epidemiological studies and dietary trials in humans suggest that alpha-linolenic acid is a major cardioprotective nutrient.</description><subject>alpha-Linolenic Acid</subject><subject>alpha-Linolenic Acid - metabolism</subject><subject>alpha-Linolenic Acid - therapeutic use</subject><subject>Biological Markers</subject><subject>Biomarkers - blood</subject><subject>canola oil</subject><subject>Cardiovascular Diseases</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>Coronary Artery Disease</subject><subject>Coronary Artery Disease - metabolism</subject><subject>Coronary Artery Disease - prevention & control</subject><subject>Diet</subject><subject>Dietary Supplements</subject><subject>essential fatty acid</subject><subject>Female</subject><subject>Food and Nutrition</subject><subject>Humans</subject><subject>Life Sciences</subject><subject>Male</subject><subject>myocardial infarction</subject><subject>Prognosis</subject><subject>purslane</subject><subject>Sensitivity and Specificity</subject><subject>walnut</subject><issn>0939-4753</issn><issn>1590-3729</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMoWqs_QdmT2MPaZPO1OUkpaoWCB_Uc8rU0st3UZFvw37vbLfXoaWB4Zt6ZB4AbBB8QRGz6DgUWOeEU30MyKSHEPEcnYISogDnmhTgFoyNyAS5T-uoZiMk5uEAUY1hwNgLTWb1Zqbz2Tahd402mjLeZamxmQgyNij_ZyqnYZtYnp5K7AmeVqpO7PtQx-Hx--pgv8uXby-t8tswNIbzNOWeYco1LpInm2HKDiBUF5aosBOSYYE0o0rbiViktuCKMVlhjzgqjqHB4DCbD3pWq5Sb6dXeJDMrLxWwp-173jKCY8B3q2LuB3cTwvXWplWufjKtr1biwTZKxEjHWvT4GdABNDClFVx03Iyh7q3JvVfbKJCRyb1X2AbeHgK1eO_s3ddDYAY8D4DolO--iTMa7xjjrozOttMH_E_ELN9OEBA</recordid><startdate>20040601</startdate><enddate>20040601</enddate><creator>de Lorgeril, M.</creator><creator>Salen, P.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>20040601</creationdate><title>Alpha-linolenic acid and coronary heart disease</title><author>de Lorgeril, M. ; Salen, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-776357b381b4b73d7c14d9257a82907343b451bdf7daab97a465f3b3762ca59e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>alpha-Linolenic Acid</topic><topic>alpha-Linolenic Acid - metabolism</topic><topic>alpha-Linolenic Acid - therapeutic use</topic><topic>Biological Markers</topic><topic>Biomarkers - blood</topic><topic>canola oil</topic><topic>Cardiovascular Diseases</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>Coronary Artery Disease</topic><topic>Coronary Artery Disease - metabolism</topic><topic>Coronary Artery Disease - prevention & control</topic><topic>Diet</topic><topic>Dietary Supplements</topic><topic>essential fatty acid</topic><topic>Female</topic><topic>Food and Nutrition</topic><topic>Humans</topic><topic>Life Sciences</topic><topic>Male</topic><topic>myocardial infarction</topic><topic>Prognosis</topic><topic>purslane</topic><topic>Sensitivity and Specificity</topic><topic>walnut</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Lorgeril, M.</creatorcontrib><creatorcontrib>Salen, P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Nutrition, metabolism, and cardiovascular diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Lorgeril, M.</au><au>Salen, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alpha-linolenic acid and coronary heart disease</atitle><jtitle>Nutrition, metabolism, and cardiovascular diseases</jtitle><addtitle>Nutr Metab Cardiovasc Dis</addtitle><date>2004-06-01</date><risdate>2004</risdate><volume>14</volume><issue>3</issue><spage>162</spage><epage>169</epage><pages>162-169</pages><issn>0939-4753</issn><eissn>1590-3729</eissn><abstract>Abstract
To summarize our present knowledge about vegetable omega-3 fatty acids.
Alpha-linolenic acid (ALA) is one of the two essential fatty acids in humans. Epidemiological studies and dietary trials strongly suggest that this fatty acid is important in relation with the pathogenesis (and prevention) of coronary heart disease. Like other n-3 fatty acids from marine origin, it may prevent cardiac arrhythmias and sudden cardiac death. The optimal dietary intake of alpha-linolenic acid seems to be about 2 g
per day or 0.6 to 1% of total energy intake. Obtaining an optimal ratio of the two essential fatty acids, linoleic and alpha-linolenic acids —
ie a ratio of less than 4 to 1 in the diet — is a major issue. The main sources of alpha-linolenic acid for the European population should be canola oil (and canola-oil based margarine if available), nuts (English walnut), ground linseeds and green leafy vegetables such as purslane.
Epidemiological studies and dietary trials in humans suggest that alpha-linolenic acid is a major cardioprotective nutrient.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>15330276</pmid><doi>10.1016/S0939-4753(04)80037-1</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0939-4753 |
| ispartof | Nutrition, metabolism, and cardiovascular diseases, 2004-06, Vol.14 (3), p.162-169 |
| issn | 0939-4753 1590-3729 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_00395347v1 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | alpha-Linolenic Acid alpha-Linolenic Acid - metabolism alpha-Linolenic Acid - therapeutic use Biological Markers Biomarkers - blood canola oil Cardiovascular Diseases Cardiovascular Diseases - prevention & control Coronary Artery Disease Coronary Artery Disease - metabolism Coronary Artery Disease - prevention & control Diet Dietary Supplements essential fatty acid Female Food and Nutrition Humans Life Sciences Male myocardial infarction Prognosis purslane Sensitivity and Specificity walnut |
| title | Alpha-linolenic acid and coronary heart disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T05%3A13%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Alpha-linolenic%20acid%20and%20coronary%20heart%20disease&rft.jtitle=Nutrition,%20metabolism,%20and%20cardiovascular%20diseases&rft.au=de%20Lorgeril,%20M.&rft.date=2004-06-01&rft.volume=14&rft.issue=3&rft.spage=162&rft.epage=169&rft.pages=162-169&rft.issn=0939-4753&rft.eissn=1590-3729&rft_id=info:doi/10.1016/S0939-4753(04)80037-1&rft_dat=%3Cproquest_hal_p%3E66816670%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=66816670&rft_id=info:pmid/15330276&rft_els_id=S0939475304800371&rfr_iscdi=true |